Preprint > Page 14
  • bioRxiv  ·  September 22, 2024  ·  Preprint

    Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair for somatic benchmarks.

    Jennifer H. McDaniel, Vaidehi Patel, Nathan D. Olson, Hua-Jun He, Zhiyong He, Anthony Schmitt, Kristin Sikkink, Fritz Sedlazeck, Harsha Doddapaneni, Shalini N. Jhangiani, Donna M. Muzny, Marie-Claude Gingras, Heer Mehta, Luis F. Paulin, Alex R. Hastie, Hung-Chun Yu, Victor Weigman, Alison Rojas, Katie Kennedy, Jamie Remington, Isai Gonzalez, Mitch Sudkamp, Kelly Wiseman, Bryan Lajoie, Shawn Levy, Miten Jain, Stuart Akeson, Giuseppe Narzisi, Zoe Steinsnyder, Catherine Reeves, Jennifer Shelton, Sarah B. Kingan, Christine Lambert, Primo Bayabyan, Aaron M. Wenger, Ian J. McLaughlin, Aaron Adamson, Christopher Kingsley, Melanie Wescott, Young Kim, Benedict Paten, Jimin Park, Ivo Violich, Karen H. Miga, Joshua Gardner, Brandy McNulty, Gail Rosen, Rajiv McCoy, Lesley Chapman Hannah, Doron Lipson, Hila Benjamin, Nika Iremadze, Ilya Soifer, Stephen Eacker, Mary Wood, Erin Cross, Greg Husar, Stephen Gross, Michael Vernich, Mikhail Komogorov, Tanveer Ahmad, Ayse Keskus, Asher Bryant, Francoise Thibaud-Nissen, Jonathan Trow, Justin Wagner, Chunlin Xiao, Andrew S Liss, Justin M. Zook

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  • bioRxiv  ·  August 27, 2024  ·  Preprint

    Type 1 interferon perturbates clonal competition by reshaping human blood development.

    Chhiring Lama, Danielle Isakov, Shira Rosenberg, Miguel Quijada-Alamo, Mirca S Saurty-Seerunghen, Sara Moein, Tsega-Ab Abera, Olivia Sakaguchi, Mansi Totwani, Grace Freed, Chi-Lam Poon, Neelang Parghi, Andrea Kubas-Meyer, Amy X. Xie, Mohamed Omar, Daniel Choi, Franco Castillo-Tokumori, Ghaith Abu-Zeinah, Alicia Dillard, Nathaniel D Omans, Neville N Dusaj, Paulina Chamely, Eleni Mimitou, Peter Smibert, Heidi E. Kosiorek, Amylou C. Dueck, Rona Weinberg, Ronan Chaligne, Bridget Marcellino, Luigi Marchionni, Sanjay Patel, Paul D. Simonson, Dan A. Landau, Elvin Wagenblast, Ronald Hoffman, Anna S Nam

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  • bioRxiv  ·  July 19, 2024  ·  Preprint

    ALS molecular subtypes are a combination of cellular, genetic, and pathological features learned by deep multiomics classifiers.

    Kathryn ONeill, Regina Shaw, Isobel Bolger, NYGC ALS Consortium, Oliver H Tam, Hemali Phatnani, Molly Gale Hammell

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  • bioRxiv  ·  June 12, 2024  ·  Preprint

    Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database.

    Sanna Gudmundsson, Moriel Singer-Berk, Sarah L. Stenton, Julia K. Goodrich, Michael W. Wilson, Jonah Einson, Nicholas A Watts, Genome Aggregation Database Consortium, Tuuli Lappalainen, Heidi L. Rehm, Daniel G. MacArthur, Anne O’Donnell-Luria

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  • bioRxiv  ·  May 31, 2024  ·  Preprint

    Systems genomics of salinity stress response in rice.

    Sonal Gupta, Simon C. Groen, Maricris L. Zaidem, Andres Godwin C. Sajise, Irina Calic, Mignon A. Natividad, Kenneth L. McNally, Georgina V. Vergara, Rahul Satija, Steven J. Franks, Rakesh K. Singh, Zoé Joly-Lopez, Michael D. Purugganan

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  • bioRxiv  ·  May 20, 2024  ·  Preprint

    Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome.

    Saravanan Ganesan, Rebecca M. Murray, Jesus Sotelo, Elliot O Eton, Kouhei Takashima, Theo Botella, Kai Beattie, Alyssa C. Indart, Nada Chraiki, Carolyne Croizier, Franco Izzo, Catherine Potenski, Samuele Marro, Zhijie Wu, Shouguo Gao, Neal S. Young, John D. Blair, Rahul Satija, Benjamin Terrier, Mael Heiblig, Eirini P Papapetrou, Pierre Sujobert, Olivier Kosmider, David B. Beck and Dan A Landau

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  • bioRxiv  ·  May 14, 2024  ·  Preprint

    Low copy CRISPR-Cas13d mitigates collateral RNA cleavage.

    Sydney K. Hart, Hans-Hermann Wessels, Alejandro Méndez-Mancilla, Simon Müller, Gediminas Drabavicius, Olivia Choi, Neville E. Sanjana

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  • arXiv  ·  April 29, 2024  ·  Preprint

    A Universal Metric of Dataset Similarity for Cross-silo Federated Learning.

    Ahmed Elhussein and Gamze Gürsoy

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  • bioRxiv  ·  April 26, 2024  ·  Preprint

    Tissue and cellular spatiotemporal dynamics in colon aging.

    Aidan C. Daly, Francesco Cambuli, Tarmo Äijö, Britta Lötstedt, Nemanja Marjanovic, Olena Kuksenko, Matthew Smith-Erb, Sara Fernandez, Daniel Domovic, Nicholas Van Wittenberghe, Eugene Drokhlyansky, Gabriel K Griffin, Hemali Phatnani, Richard Bonneau, Aviv Regev, Sanja Vicković

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  • bioRxiv  ·  April 20, 2024  ·  Preprint

    Ultra-secure storage and analysis of genetic data for the advancement of precision medicine.

    Jacob Blindenbach, Jiayi Kang, Seungwan Hong, Caline Karam, Thomas Lehner, Gamze Gürsoy

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