Preprint Archives - Page 12 of 24 - New York Genome Center

arXiv · February 12, 2025 · Preprint

PLayer-FL: A Principled Approach to Personalized Layer-wise Cross-Silo Federated Learning.

Ahmed Elhussein, Gamze Gürsoy

medRxiv · January 13, 2025 · Preprint

Regulation of protein abundance in normal human tissues.

Huaying Fang, Lihua Jiang, Felipe da Veiga Leprevost, Ruiqi Jian, Joanne Chan, Dafni Glinos, Tuuli Lappalainen, Alexey I. Nesvizhskii, Alexander P. Reiner, GTEx Consortium, Michael Snyder, Hua Tang

Lappalainen Lab

bioRxiv · January 11, 2025 · Preprint

Enhancer Dynamics and Spatial Organization Drive Anatomically Restricted Cellular States in the Human Spinal Cord.

Elena K. Kandror, Anqi Wang, Mathieu Carriere, Alexis Peterson, Will Liao, Andreas Tjärnberg, Jun Hou Fung, Krishnaa T. Mahbubani, Jackson Loper, William Pangburn, Yuchen Xu, Kourosh Saeb-Parsy, Raul Rabadan, Tom Maniatis, Abbas H. Rizvi

Maniatis Lab

bioRxiv · January 2, 2025 · Preprint

Single-cell mapping of regulatory DNA:Protein interactions.

Wei-Yu Chi, Sang-Ho Yoon, Levan Mekerishvili, Saravanan Ganesan, Catherine Potenski, Franco Izzo, Dan Landau, Ivan Raimondi

Landau Lab

medRxiv · December 8, 2024 · Preprint

Epigenome-wide Association Analysis of Mitochondrial Heteroplasmy Provides Insight into Molecular Mechanisms of Disease.

Meng Lai, Kyeezu Kim, Yinan Zheng, Christina A. Castellani, Scott M. Ratliff, Mengyao Wang, Xue Liu, Jeffrey Haessler, Tianxiao Huan, Lawrence F. Bielak, Wei Zhao, Roby Joehanes, Jiantao Ma, Xiuqing Guo, JoAnn E. Manson, Megan L. Grove, Jan Bressler, Kent D. Taylor, Tuuli Lappalainen, Silva Kasela, Thomas W. Blackwell, Nicole J. Lake, Jessica D. Faul, Kendra R. Ferrier, Lifang Hou, Charles Kooperberg, Alexander P. Reiner, Kai Zhang, Patricia A. Peyser, Myriam Fornage, Eric Boerwinkle, Laura M. Raffield, April P. Carson, Stephen S. Rich, Yongmei Liu, Daniel Levy, Jerome I. Rotter, Jennifer A. Smith, Dan E. Arking, Chunyu Liu, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.

Lappalainen Lab

medRxiv · December 13, 2024 · Preprint

Deriving Mendelian Randomization-based Causal Networks of Brain Imaging Phenotypes and Bipolar Disorder.

Shane O’Connell, Brielin C. Brown, Dara M. Cannon, Pilib Ó Broin, David A. Knowles, Nadine Parker, Dag Alnæs, Lars T. Westlye, Saikat Banerjee, Leila Nabulsi, Emma Corley, Ole A. Andreassen, Niamh Mullins

Knowles Lab

medRxiv · December 8, 2024 · Preprint

Leveraging functional annotations to map rare variants associated with Alzheimer’s disease with gruyere.

Anjali Das, Chirag Lakhani, Chloé Terwagne, Jui-Shan Lin, Tatsuhiko Naito, Towfique Raj, David A Knowles

Knowles Lab

bioRxiv · November 27, 2024 · Preprint

Paired CRISPR screens to map gene regulation in cis and trans.

Xinhe Xue, Zoran Z. Gajic, Christina M. Caragine, Mateusz Legut, Conor Walker, James Y.S. Kim, Xiao Wang, Rachel E. Yan, Hans-Hermann Wessels,Congyi Lu, Neil Bapodra,Gamze Gürsoy, Neville E. Sanjana

Sanjana Lab

bioRxiv · November 14, 2024 · Preprint

Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord.

John F. Tuddenham, Masashi Fujita, Anthony Khairallah, Claire Harbison, Xena E. Flowers, Guillermo Coronas-Samano, Silas Maniatis, Aidan Daly, Julie A. Schneider, Andrew F. Teich, Jean Paul G. Vonsattel, Peter A. Sims, Wassim Elyaman, Elizabeth M. Bradshaw, Hemali Phatnani, Neil Shneider, David A. Bennett, Philip L. De Jager, Serge Przedborski, Vilas Menon and Marta Olah

Phatnani Lab

Neurodegenerative Disease

bioRxiv · October 17, 2024 · Preprint

An analysis of RNA quality metrics in human brain tissue.

Jiahe Tian, Tiffany Lam, Sophie Ross, Benjamin Ciener, Sandra Leskinen, Sharanya Sivakumar, David A Bennett, Vilas Menon, Guy M McKhann, Alexi Runnels, Andrew Teich

Scientific Collaboration & Project Management