The New York Genome Center (NYGC) is an independent, nonprofit academic research institution that serves as a multi-institutional hub for genomic research. Leveraging our strengths in whole-genome sequencing and genomic analysis, our mission is the advancement of genomic science and its application to drive novel biomedical discoveries. NYGC’s areas of focus include the development of computational and experimental genomic methods and disease-focused research to better understand the genetic basis of cancer, neurodegenerative disease, and neuropsychiatric disease. In 2020, the NYGC also has directed its expertise to COVID-19 research.

We are committed to prioritizing diversity, equity, and inclusion, which is fundamental to promoting greater collaboration, innovation, and discovery. Learn more about NYGC’s Commitment to Diversity, Equity, and Inclusion.

Nature Biotechnology. 2021 June 3.

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.

Eleni P. Mimitou, Caleb A. Lareau, Kelvin Y. Chen, Andre L. Zorzetto-Fernandes, Yuhan Hao, Yusuke Takeshima, Wendy Luo, Tse-Shun Huang, Bertrand Z. Yeung, Efthymia Papalexi, Pratiksha I. Thakore, Tatsuya Kibayashi, James Badger Wing, Mayu Hata, Rahul Satija, Kristopher L. Nazor, Shimon Sakaguchi, Leif S. Ludwig, Vijay G. Sankaran, Aviv Regev & Peter Smibert

medRxiv. 2021 June 2.

IL10RB as a key regulator of COVID-19 host susceptibility and severity.

Georgios Voloudakis, Gabriel Hoffman, Sanan Venkatesh,Kyung Min Lee, Kristina Dobrindt, James Vicari, Wen Zhang,Noam D. Beckmann, Shan Jiang, Daisy Hoagland, Jiantao Bian, Lina Gao, André Corvelo, Kelly Cho, Jennifer S. Lee, Sudha K. Iyengar,Shiuh Wen Luoh, Schahram Akbarian, Robert Striker, Themistocles L. Assimes, Eric E. Schadt, Miriam Merad, Benjamin R. tenOever, Alexander W. Charney, Kristen J. Brennand, Julie A. Lynch, John F. Fullard, Panos Roussos

Cell. 2021 May 31.

Integrated analysis of multimodal single-cell data.

Yuhan Hao, Stephanie Hao, Erica Andersen-Nissen, William M. Mauck, Shiwei Zheng, Andrew Butler, Maddie Jane Lee, Aaron J. Wilk, Charlotte Darby, Michael Zagar, Paul Hoffman, Marlon Stoeckius, Efthymia Papalexi, Eleni P. Mimitou, Jaison Jain, Avi Srivastava, Tim Stuart, Lamar B. Fleming, Bertrand Yeung, Angela J. Rogers, Juliana M. McElrath, Catherine A. Blish, Raphael Gottardo, Peter Smibert, Rahul Satija

Institutional Founding Members

Institutional Associate Members