Preprint > Page 16
  • bioRxiv  ·  July 19, 2023  ·  Preprint

    Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes.

    Samuel K. Powell, Will Liao, Callan O’Shea, Sarah Kammourh, Sadaf Ghorbani, Raymond Rigat, Rahat Elahi, PJ Michael Deans, Derek J. Le, Poonam Agarwal, Wei Qiang Seow, Kevin C. Wang, Schahram Akbarian, Kristen J. Brennand

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  • medRxiv  ·  June 29, 2023  ·  Preprint

    Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study.

    Yuxuan Wang, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Jacob A Holdcraft, Donna K Arnett, Joshua C Bis, John Blangero, Eric Boerwinkle, Donald W Bowden, Brian E Cade, Jenna C Carlson, April P Carson, Yii-Der Ida Chen, Joanne E Curran, Paul S de Vries, Susan K Dutcher, Patrick T Ellinor, James S Floyd, Myriam Fornage, Barry I Freedman, Stacey Gabriel, Soren Germer, Richard A Gibbs, Xiuqing Guo, Jiang He, Nancy Heard-Costa, Bertha Hildalgo, Lifang Hou, Marguerite R Irvin, Roby Joehanes, Robert C Kaplan, Sharon LR Kardia, Tanika N Kelly, Ryan Kim, Charles Kooperberg, Brian G Kral, Daniel Levy, Changwei Li, Chunyu Liu, Don Lloyd-Jone, Ruth JF Loos, Michael C Mahaney, Lisa W Martin, Rasika A Mathias, Ryan L Minster, Braxton D Mitchell, May E Montasser, Alanna C Morrison, Joanne M Murabito, Take Naseri, Jeffrey R O’Connell, Nicholette D Palmer, Michael H Preuss, Bruce M Psaty, Laura M Raffield, Dabeeru C Rao, Susan Redline, Alexander P Reiner, Stephen S Rich, Muagututi’a Sefuiva Ruepena, Wayne H-H Sheu, Jennifer A Smith, Albert Smith, Hemant K Tiwari, Michael Y Tsai, Karine A Viaud-Martinez, Zhe Wang, Lisa R Yanek, Wei Zhao, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Jerome I Rotter, Xihong Lin, Pradeep Natarajan, Gina M Peloso

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  • bioRxiv  ·  June 26, 2023  ·  Preprint

    Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects.

    Silva Kasela, François Aguet, Sarah Kim-Hellmuth, Brielin C. Brown, Daniel C. Nachun, Russell P. Tracy, Peter Durda, Yongmei Liu, Kent D. Taylor, W. Craig Johnson, David Van Den Berg, Stacey Gabriel, Namrata Gupta, Joshua D. Smith, Thomas W. Blackwell, Jerome I. Rotter, Kristin G. Ardlie, Ani Manichaikul, Stephen E. Rich, R. Graham Barr and Tuuli Lappalainen

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  • bioRxiv  ·  June 14, 2023  ·  Preprint

    RAVER1 interconnects lethal EMT and miR/RISC activity by the control of alternative splicing.

    Alice Wedler, Nadine Bley, Markus Glass, Simon Müller, Laura Schian, Kingsley Benjamin Obika, Marcell Lederer, Claudia Misiak, Tommy Fuchs, Marcel Koehn, Roland Jacob, Tony Gutschner, Christian Ihling, Andrea Sinz, Stefan Huettelmaier

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  • bioRxiv  ·  June 12, 2023  ·  Preprint

    In situ spatial reconstruction of distinct normal and pathological cell populations within the human adrenal gland.

    Rui Fu, Kathryn Walters, Katrina Koc, Amber Baldwin, Michael Clay, Katja Kiseljak-Vassiliades, Lauren Fishbein and Neelanjan Mukherjee

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  • bioRxiv  ·  May 30, 2023  ·  Preprint

    Genomewide paired DNA-RNAseq analyses to discover intronic splice mutation hotspots in neurological disorders.

    Yan Wang, Charlotte van Dijk, Ilia Timpanaro, Paul J. Hop, Brendan Kenna, Maarten Kooyman, Eleonora Aronica, R. Jeroen Pasterkamp, Leonard van den Berg, Johnathan Cooper-Knock, Project MinE ALS sequencing consortium, NYGC ALS consortium, Jan Veldink, Kevin Kenna

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  • bioRxiv  ·  May 17, 2023  ·  Preprint

    Oncogenic reactivation of young L1s is a hallmark of colon cancer.

    Devin Neu, Stevephen Hung, Cynthia F. Bartels, Zachary J. Faber, Katreya Lovrenert, W. Dean Pontius, Laura Morgan, Maharshi Chakraborty, Will Liao, Diana Chin, Ellen S. Hong, Jeremy Gray, View ORCID ProfileVictor Moreno, Matthew Kalady, Ulrike Peters, Berkley Gryder, Richard C. Sallari, Peter C. Scacheri

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  • bioRxiv  ·  May 15, 2023  ·  Preprint

    A comprehensive catalog of 3D genome organization in diverse human genomes facilitates understanding of the impact of structural variation on chromatin structure.

    Chong Li, Marc Jan Bonder, Sabriya Syed, Human Genome Structural Variation Consortium (HGSVC), HGSVC Functional Analysis Working Group, Michael C. Zody, Mark J.P. Chaisson, Michael E Talkowski, Tobias Marschall, Jan O Korbel, Evan E Eichler, Charles Lee, Xinghua Shi

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  • bioRxiv  ·  May 7, 2023  ·  Preprint

    The Interplay between Mutagenesis and Extrachromosomal DNA Shapes Urothelial Cancer Evolution.

    Duy D. Nguyen, William F. Hooper, Timothy R. Chu, Heather Geiger, Jennifer M. Shelton, Minita Shah, Zoe R. Goldstein, Lara Winterkorn, Michael Sigouros, Jyothi Manohar, Jenna Moyer,David Wilkes, Rahul R. Singh, Weisi Liu, Andrea Sboner, Scott T. Tagawa, David M. Nanus, Jones T. Nauseef, Cora N. Sternberg, Ana M. Molina, Douglas S. Scherr, Giorgio Ga. Inghirami, Juan Miguel Mosquera, Olivier Elemento, Nicolas Robine, Bishoy M. Faltas

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  • bioRxiv  ·  March 27, 2023  ·  Preprint

    Phospho-seq: Integrated, multi-modal profiling of intracellular protein dynamics in single cells.

    John D. Blair, Austin Hartman, Fides Zenk, Carol Dalgarno, Barbara Treutlein, Rahul Satija

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