Sanjana Lab
Neville Sanjana’s lab develops technologies to understand how human genetic variants cause disease, with applications to the immune system, nervous system and cancer. The lab employs a multi-disciplinary approach, combining genome engineering, pooled genetic screens and massively-parallel DNA synthesis, bioinformatics, single-cell multiomics, and imaging, to dissect the inner workings of the human genome and its dysfunction in autism, autoimmunity and tumor evolution. The Sanjana lab is a team of molecular engineers, biologists, immunologists, neuroscientists, computer scientists and bioscience entrepreneurs who are passionate about creating new technologies for genomics and advancing human health. The lab is also affiliated with the Department of Biology at New York University.
Neville Sanjana, PhD
Core Faculty Member, NYGC
Associate Professor of Biology, Neuroscience and Physiology, NYU
Latest News & Publications
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Cell Reports · August 16, 2024
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bioRxiv · May 14, 2024 · Preprint
Low copy CRISPR-Cas13d mitigates collateral RNA cleavage.
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Proceedings of the National Academy of Sciences of the United States of America · May 14, 2024
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.