Our Scientific Publications
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Am J Respir Crit Care Med · May 27, 2020
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Nature · May 27, 2020
Mapping and characterization of structural variation in 17,795 human genomes.
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The Lancet Psychiatry · May 20, 2020
Mental Health Delivery and Neurogenetics Discovery in Africa.
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Genome Biology · April 28, 2020
ExpansionHunter Denovo: A computational method for locating known and novel repeat expansions in short-read sequencing data.
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Genetics · April 23, 2020
Novel KITLG/SCF regulatory variants are associated with lung function in African American children with asthma.
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Nature Communications · April 20, 2020
High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange.
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Neuron · March 27, 2020
The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.
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Nature Genetics · March 23, 2020
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
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Nature Biotechnology · March 16, 2020
Massively parallel Cas13 screens reveal principles for guide RNA design.
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bioRxiv · February 24, 2020 · Preprint
An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation.
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Cell Reports · March 3, 2020
High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation.
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bioRxiv · February 11, 2020 · Preprint
Recent Ultra-rare Inherited Mutations Identify Novel Autism Candidate Risk Genes
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Nature · February 6, 2020
The evolutionary history of 2,658 cancers.
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Nature · February 5, 2020
Pan-cancer analysis of whole genomes.
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Neurochem Res. · February 4, 2020
Dynamic Lamin B1-Gene Association During Oligodendrocyte Progenitor Differentiation.
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Genome Biology · December 23, 2019
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression.
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Science Translational Medicine · December 18, 2019
Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology.
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Scientific Reports · December 13, 2019
Deep sequencing of 3 cancer cell lines on 2 sequencing platforms
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PLoS Genet · December 13, 2019
Leveraging allelic imbalance to refine fine-mapping for eQTL studies.
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Cell · December 12, 2019
Toward a Common Coordinate Framework for the Human Body.
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Nature Neuroscience · November 25, 2019
Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.