Our Scientific Publications
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Research Square · March 2, 2021 · Preprint
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Nature Genetics · March 1, 2021
Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens.
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Science · February 25, 2021
Haplotype-resolved diverse human genomes and integrated analysis of structural variation
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bioRxiv · February 11, 2021 · Preprint
A like-for-like comparison of lightweight-mapping pipelines for single-cell RNA-seq data pre-processing.
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eLife · February 11, 2021
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types.
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Nature · February 10, 2021
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
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Journal of Neuroscience · February 3, 2021
Reduced Motivation in Perinatal Fluoxetine-Treated Mice: A Hypodopaminergic Phenotype.
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The Journal of Neuroscience · February 3, 2021
Reduced motivation in perinatal fluoxetine treated mice: a hypodopaminergic phenotype.
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Cell Reports · February 2, 2021
Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway.
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Investigative Ophthalmology & Visual Science · February 1, 2021
The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans.
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Genome Biology · January 26, 2021
Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.
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American Journal of Human Genetics · January 25, 2021
De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis.
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Bioinformatics · January 20, 2021
Compression of quantification uncertainty for scRNA-seq counts.
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bioRxiv · January 19, 2021 · Preprint
Accounting for fragments of unexpected origin improves transcript quantification in RNA-seq simulations focused on increased realism.
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bioRxiv · January 14, 2021 · Preprint
An Effector Index to Predict Causal Genes at GWAS Loci
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Trials · January 14, 2021
The NYCKidSeq project: study protocol for a randomized controlled trial incorporating genomics into the clinical care of diverse New York City children.
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bioRxiv · January 11, 2021 · Preprint
The landscape of human brain immune response in patients with severe COVID-19.
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PLOS Computational Biology · January 11, 2021
Preprocessing choices affect RNA velocity results for droplet scRNA-seq data.
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Current Opinion in Genetics & Development · January 9, 2021
Spatially resolved transcriptomics and its applications in cancer.
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Nature Structural & Molecular Biology · January 4, 2021
Structural and functional characterization of the Spo11 core complex.
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Nature Methods · January 4, 2021
Quantum computing at the frontiers of biological sciences.