Our Scientific Publications
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bioRxiv · May 23, 2024 · Preprint
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Biology · May 15, 2024
1,25-Dihydroxyvitamin D3 Suppresses Prognostic Survival Biomarkers Associated with Cell Cycle and Actin Organization in a Non-Malignant African American Prostate Cell Line.
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bioRxiv · May 20, 2024 · Preprint
Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome.
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bioRxiv · May 14, 2024 · Preprint
Low copy CRISPR-Cas13d mitigates collateral RNA cleavage.
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Proceedings of the National Academy of Sciences of the United States of America · May 14, 2024
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.
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Cell · May 9, 2024
The future of rapid and automated single-cell data analysis using reference mapping.
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Communications Medicine · May 9, 2024
A comprehensive AI model development framework for consistent Gleason grading.
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Nature · May 8, 2024
Mapping genotypes to chromatin accessibility profiles in single cells.
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Cell Genomics · May 1, 2024
The broken Alzheimer’s disease genome.
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bioRxiv · April 20, 2024 · Preprint
Ultra-secure storage and analysis of genetic data for the advancement of precision medicine.
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arXiv · April 29, 2024 · Preprint
A Universal Metric of Dataset Similarity for Cross-silo Federated Learning.
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bioRxiv · April 26, 2024 · Preprint
Tissue and cellular spatiotemporal dynamics in colon aging.
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JAMA Psychiatry · April 17, 2024
Examining Sex Differences in Autism Heritability.
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Nature Reviews Genetics · April 12, 2024
SIMPLE-seq to decode DNA methylation dynamics in single cells.
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Acta Neuropathologica · April 10, 2024
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease.
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bioRxiv · April 10, 2024 · Preprint
Recalibrating differential gene expression by genetic dosage variance prioritizes functionally relevant genes.
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Cancer Cell · April 2, 2024
Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma.
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NPJ Genomic Medicine · March 27, 2024
Advancing access to genome sequencing for rare genetic disorders: recent progress and call to action.
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Science Advances · March 22, 2024
Childhood cancer mutagenesis caused by transposase-derived PGBD5.
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NPJ Genomic Medicine · March 22, 2024
Genomic analysis of 116 autism families strengthens known risk genes and highlights promising candidates.
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STAR Protocols · March 20, 2024
GoT-Splice protocol for multi-omics profiling of gene expression, cell-surface proteins, mutational status, and RNA splicing in human cells.