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Science & Technology

Where Vision Meets Innovation

Our collaborative research programs unite leading experts from diverse fields to advance our understanding of the genetic foundations of biology and disease, while exploring cutting-edge technological innovations.

Collaborative Research Programs

Groundbreaking Research

We cultivate a diverse research community dedicated to advancing the understanding of genomic science and the treatment of human disease.

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Faculty Labs

Innovators in Action

Discover the diverse expertise driving our research. From unraveling disease mechanisms to advancing innovative technologies, our faculty labs are at the forefront of the NYGC’s scientific endeavors.

All Faculty Labs
  • Gamze Gürsoy headshot Gürsoy Lab
  • Marcin Imielinsky headshot Imieliński Lab
  • Ivan Iossifov headshot Iossifov Lab
  • David A Knowles headshot Knowles Lab
  • Dan Landau headshot Landau Lab
  • Ren Lab
  • Hemali Phatnani headshot Phatnani Lab
  • Neville Sanjana headshot Sanjana Lab
  • Rahul Satija headshot Satija Lab
  • Sanja Vicković headshot Vicković Lab
  • Mike Wigler headshot Wigler Lab
  • Chenxu Zhu headshot Zhu Lab
  • Sam Aparicio headshot Aparicio Lab
  • Mary-Claire King headshot King Lab
  • Tuuli Lappalainen headshot Lappalainen Lab
  • Tom Maniatis headshot Maniatis Lab
  • Simon Tavaré headshot Tavaré Lab
  • Harold Varmus headshot Varmus Lab
  • Onyinye Balogun headshot Balogun Lab
  • L. Davis Lab
  • Melissa Davis headshot M. Davis Lab
  • Stephan Sanders headshot Sanders Lab
  • Tarjinder Singh headshot Singh Lab
Technology Platforms

Innovative Technology Platforms

Our multidisciplinary team of scientists, engineers, and NYGC faculty come together to explore and test innovative genomic tools and technologies to drive progress within our center and the broader scientific community.

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Recent Publications

Publications Archive
  • Proceedings of the National Academy of Sciences of the United States of America  ·  October 28, 2025

    Genetic regulation of the estrogen receptor and inherited predisposition to breast cancer.

    Sarah B Pierce, Hannah Kortbawi, Suleyman Gulsuner, Jessica B Mandell, Ming K Lee, Tom Walsh, Mary-Claire King.

    Cancer
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  • bioRxiv  ·  October 21, 2025  ·  Preprint

    APOBEC3A-Induced DNA Damage Drives Polymerase Theta Dependency and Synthetic Lethality in Cancer.

    Abhishek Bose, Weisi Liu, Paul Yoo, Alina Sami, Michal T Boniecki, Madhura Deshpande, Mohamed Osman, Duy Nguyen, Urko D. Castillo, Paraskevi Giannakakou, Bhavneet Bhinder, William Hooper, Olivier Elemento, Nicolas Robine, Milaid Granadillo Rodrigue, Jeannine Gerhardt, Kent W. Mouw, Linda Chelico, Bishoy M. Faltas.

    Cancer
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  • Nature Neuroscience  ·  October 21, 2025

    TDP-43 loss induces cryptic polyadenylation in ALS/FTD.

    Sam Bryce-Smith, Anna-Leigh Brown, Max Z. Y. J. Chien, Dario Dattilo, Puja R. Mehta, Francesca Mattedi, Simone Barattucci, Alla Mikheenko, Matteo Zanovello, Flaminia Pellegrini, Sara Emad El-Agamy, Matthew Yome, Sarah E. Hill, Yue A. Qi, Kai Sun, Eugeni Ryadnov, Yixuan Wan, NYGC ALS Consortium, Jose Norberto S. Vargas, Nicol Birsa, Towfique Raj, Jack Humphrey, Matthew Keuss, Oscar G. Wilkins, Michael Ward, Maria Secrier & Pietro Fratta.

    Phatnani Lab Neurodegenerative Disease
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Publications Archive
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