Sanjana Lab
Neville Sanjana’s lab develops technologies to understand how human genetic variants cause disease, with applications to the immune system, nervous system and cancer. The lab employs a multi-disciplinary approach, combining genome engineering, pooled genetic screens and massively-parallel DNA synthesis, bioinformatics, single-cell multiomics, and imaging, to dissect the inner workings of the human genome and its dysfunction in autism, autoimmunity and tumor evolution. The Sanjana lab is a team of molecular engineers, biologists, immunologists, neuroscientists, computer scientists and bioscience entrepreneurs who are passionate about creating new technologies for genomics and advancing human health. The lab is also affiliated with the Department of Biology at New York University.
Neville Sanjana, PhD
Core Faculty Member, NYGC
Associate Professor of Biology, Neuroscience and Physiology, NYU

Latest News & Publications
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Nature Communications · July 29, 2025
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Scandinavian Journal of Immunology · July 28, 2025
Multiparametric Optimization of Human Primary B-Cell Cultures Using Design of Experiments.
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biorXiv · May 5, 2025 · Preprint
CRISPRi perturbation screens and eQTLs provide complementary and distinct insights into GWAS target genes.
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