bioRxiv
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February 11, 2026 ·
Preprint
Identification of target genes and regulatory networks for bone mineral density GWAS loci through systematic targeting and inhibition.
Lappalainen Lab
Tuuli Lappalainen’s lab studies functional genetic variation in human populations. It is particularly interested in regulatory variation affecting the transcriptome, as well as cellular mechanisms underlying genetic associations to disease. The lab integrates computational analysis of genomic and transcriptomic data with population genetic and experimental analysis.
Tuuli Lappalainen, PhD
Senior Associate Faculty Member, NYGC
Director, National Genomics Infrastructure, SciLifeLab; Professor, KTH School of Engineering Sciences in Chemistry, Biotechnology and Health; Former Assistant Professor, Department of Systems Biology, Columbia University
Latest News & Publications
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medRxiv · January 30, 2026 · Preprint
Integrating multi-omic QTLs and predictive models reveals regulatory architectures at immune related GWAS loci in CD4+ T cells.
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medRxiv · January 16, 2026 · Preprint
Multi-molecular scores map process-specific polygenic diabetes risk to atherosclerosis, cardiometabolic diseases, and vascular complications.
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