The New York Genome Center is building upon its extensive collaborative work in autism genomic research to study a range of related neuropsychiatric disorders with overlapping molecular architecture, including schizophrenia and bipolar disorder.
The Neuropsychiatric Disease Working Group, led by Thomas Lehner, PhD, MPH, NYGC brings together researchers from our Institutional Founding Members, NYGC faculty, senior faculty, NYGC technology development and computational scientists, and affiliate members to discuss the underlying disease mechanisms in neuropsychiatric disease. The group is building off the large dataset produced by NYGC as part of the Centers for Common Disease Genomics, funded by the NHGRI. As part of this effort, NYGC generated whole genome sequencing data on over 37,000 individuals from families with at least one member affected by autism spectrum disorder. Currently the group is working on a number of initiatives studying the biological underpinnings of neuropsychiatric disorders including bipolar disorder, schizophrenia and other psychosis-related disorders.