Publication > Page 11
  • Cell Reports  ·  August 16, 2024

    Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.

    Platon Megagiannis, Yuan Mei, Rachel E Yan, Lin Yuan, Jonathan J Wilde, Hailey Eckersberg, Rahul Suresh, Xinzhu Tan, Hong Chen, W Todd Farmer, Kuwook Cha, Phuong Uyen Le, Helene Catoire, Daniel Rochefort, Tony Kwan, Brian A Yee, Patrick Dion, Arjun Krishnaswamy, Jean-Francois Cloutier, Stefano Stifani, Kevin Petrecca, Gene W Yeo, Keith K Murai, Guoping Feng, Guy A Rouleau, Trey Ideker, Neville E Sanjana, Yang Zhou

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  • Muscle & Nerve  ·  August 9, 2024

    Mitochondrial genome variants associated with amyotrophic lateral sclerosis and their haplogroup distribution.

    Marcelo R. S. Briones PhD, João H. Campos PhD, Renata C. Ferreira PhD, Lisa Schneper PhD, Ilda M. Santos MSc, Fernando M. Antoneli PhD, NYGC ALS Consortium, James R. Broach PhD

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  • Cell  ·  August 8, 2024

    Multiplexed single-cell characterization of alternative polyadenylation regulators.

    Madeline H Kowalski, Hans-Hermann Wessels, Johannes Linder, Carol Dalgarno, Isabella Mascio, Saket Choudhary, Austin Hartman, Yuhan Hao, Anshul Kundaje, Rahul Satija

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  • Nature Communications  ·  August 8, 2024

    Multi-omic analysis of Huntington’s disease reveals a compensatory astrocyte state.

    Fahad Paryani, Ji-Sun Kwon, Christopher W. Ng, Kelly Jakubiak, Nacoya Madden, Kenneth Ofori, Alice Tang, Hong Lu, Shengnan Xia, Juncheng Li, Aayushi Mahajan, Shawn M. Davidson, Anna O. Basile, Caitlin McHugh, Jean Paul Vonsattel, Richard Hickman, Michael C. Zody, David E. Housman, James E. Goldman, Andrew S. Yoo, Vilas Menon & Osama Al-Dalahmah

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  • Scientific Reports  ·  August 1, 2024

    A methylation risk score for chronic kidney disease: a HyperGEN study.

    Alana C. Jones, Amit Patki, Vinodh Srinivasasainagendra, Bertha A. Hidalgo, Hemant K. Tiwari, Nita A. Limdi, Nicole D. Armstrong, Ninad S. Chaudhary, Bré Minniefield, Devin Absher, Donna K. Arnett, Leslie A. Lange, Ethan M. Lange, Bessie A. Young, Clarissa J. Diamantidis, Stephen S. Rich, Josyf C. Mychaleckyj, Jerome I. Rotter, Kent D. Taylor, Holly J. Kramer, Russell P. Tracy, Peter Durda, Silva Kasela, Tuuli Lappalinen, Yongmei Liu, W. Craig Johnson, David J. Van Den Berg, Nora Franceschini, Simin Liu, Charles P. Mouton, Parveen Bhatti, Steve Horvath, Eric A. Whitsel & Marguerite R. Irvin

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  • Genome Biology  ·  July 18, 2024

    Leveraging neighborhood representations of single-cell data to achieve sensitive DE testing with miloDE.

    Alsu Missarova, Emma Dann, Leah Rosen, Rahul Satija & John Marioni

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  • American Journal of Human Genetics  ·  July 11, 2024

    The DARC side of genetics in cancer: Breast cancer disparities.

    Rachel Martini, Melissa B. Davis

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  • The EMBO Journal  ·  July 1, 2024

    YTHDC1 m6A-dependent and m6A-independent functions converge to preserve the DNA damage response.

    Daniel Elvira-Blázquez, José Miguel Fernández-Justel, Aida Arcas, Luisa Statello, Enrique Goñi, Jovanna González, Benedetta Ricci, Sara Zaccara, Ivan Raimondi, Maite Huarte

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  • BMC Genomics  ·  June 29, 2024

    Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS.

    Tess D. Pottinger, Joshua E. Motelow, Gundula Povysil, Cristiane A. Martins Moreno, Zhong Ren, Hemali Phatnani, The New York Genome Center ALS Sequencing Consortium, Timothy J. Aitman, Javier Santoyo-Lopez, Scottish Genomes Partnership, Hiroshi Mitsumoto, ALS COSMOS Study Group, PLS COSMOS Study Group, GTAC Investigators, David B. Goldstein & Matthew B. Harms

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  • Journal of Biomedical Informatics  ·  June 25, 2024

    Privacy-preserving model evaluation for logistic and linear regression using homomorphically encrypted genotype data.

    Seungwan Hong, Yoolim A Choi, Daniel S Joo, Gamze Gürsoy

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