Preprint > Page 19
  • bioRxiv  ·  May 18, 2022  ·  Preprint

    Jak2V617F Reversible Activation Shows an Essential Requirement for Jak2V617F in Myeloproliferative Neoplasms.

    Andrew Dunbar, Robert L. Bowman, Young Park, Franco Izzo, Robert M. Myers, Abdul Karzai, Won Jun Kim, Inés Fernández Maestre, Michael R. Waarts, Abbas Nazir, Wenbin Xiao, Max Brodsky, Mirko Farina, Louise Cai, Sheng F. Cai, Benjamin Wang, Wenbin An, Julie L. Yang, Shoron Mowla, Shira E. Eisman, Tanmay Mishra, Remie Houston, Emily Guzzardi, Anthony R. Martinez Benitez, Aaron Viny, Richard Koche, Dan A. Landau, Ross L. Levine

    Landau Lab Biology, Genomics & Technology
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  • bioRxiv  ·  May 11, 2022  ·  Preprint

    Integrated Single-Cell Genotyping and Chromatin Accessibility Charts JAK2V617F Human Hematopoietic Differentiation.

    Robert M. Myers, Franco Izzo, Sanjay Kottapalli, Tamara Prieto, Andrew Dunbar, Robert L. Bowman, Eleni P. Mimitou, Maximilian Stahl, Sebastian El Ghaity-Beckley, JoAnn Arandela, Ramya Raviram, Saravanan Ganesan, Levan Mekerishvili, Ronald Hoffman, Ronan Chaligné, Omar Abdel-Wahab, Peter Smibert, Bridget Marcellino, Ross L. Levine, Dan A. Landau

    Landau Lab Biology, Genomics & Technology
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  • bioRxiv  ·  April 19, 2022  ·  Preprint

    Predicting A/B compartments from histone modifications using deep learning.

    Suchen Zheng, Nitya Thakkar, Hannah L. Harris, Megan Zhang, Susanna Liu, Mark Gerstein, Erez Lieberman-Aiden, M. Jordan Rowley, William Stafford Noble, Gamze Gürsoy, Ritambhara Singh

    Biology, Genomics & Technology
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  • bioRxiv  ·  March 18, 2022  ·  Preprint

    Integrated protein and transcriptome high-throughput spatial profiling.

    Nir Ben-Chetrit, Xiang Niu, Ariel D. Swett, Jesus Sotelo, Maria S. Jiao, Patrick Roelli, Marlon Stoeckius, Dan A. Landau

    Landau Lab Cancer Biology, Genomics & Technology
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  • bioRxiv  ·  March 8, 2022  ·  Preprint

    Nanobody-tethered transposition allows for multifactorial chromatin profiling at single-cell resolution.

    Tim Stuart, Stephanie Hao, Bingjie Zhang, Levan Mekerishvili, Dan A Landau, Silas Maniatis, Rahul Satija, and Ivan Raimondi

    Satija Lab
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  • bioRxiv  ·  February 24, 2022  ·  Preprint

    Dictionary learning for integrative, multimodal, and scalable single-cell analysis.

    Yuhan Hao, Tim Stuart, Madeline Kowalski, Saket Choudhary, Paul Hoffman, Austin Hartman, Avi Srivastava, Gesmira Molla, Shaista Madad, Carlos Fernandez-Granda, Rahul Satija

    Satija Lab
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  • bioRxiv  ·  February 2, 2022  ·  Preprint

    Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq.

    Hans-Hermann Wessels, Alejandro Mendez-Mancilla, Efthymia Papalexi, William M Mauck, Lu Lu, John A Morris, Eleni P Mimitou, Peter Smibert, Neville E Sanjana, Rahul Satija

    Sanjana Lab Satija Lab Computational Biology Lab
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  • bioRxiv  ·  January 20, 2022  ·  Preprint

    Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring.

    Adam J. Widman, Minita Shah, Nadia Ogaard, Cole C. Khamnei, Amanda Frydendahl, Aditya Deshpande, Anushri Arora, Mingxuan Zhang, Daniel Halmos, Jake Bass, Theophile Langanay, Srinivas Rajagopalan, Zoe Steinsnyder, Will Liao, Mads Heilskov Rasmussen, Sarah Ostrup Jensen, Jesper Nors, Christina Therkildsen, Jesus Sotelo, Ryan Brand, Ronak H. Shah, Alexandre Pellan Cheng, Colleen Maher, Lavinia Spain, Kate Krause, Dennie T. Frederick, Murtaza S. Malbari, Melissa Marton, Dina Manaa, Lara Winterkorn, Margaret K. Callahan, Genevieve Boland, Jedd D. Wolchok, Ashish Saxena, Samra Turajlic, Marcin Imielinski, Michael F. Berger, Nasser K. Altorki, Michael A. Postow, Nicolas Robine, Claus Lindbjerg Andersen, Dan A. Landau
    Imieliński Lab Landau Lab Cancer Biology, Genomics & Technology Computational Biology Lab
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  • bioRxiv  ·  January 18, 2022  ·  Preprint

    Non-Coding Genetic Analysis Implicates Interleukin 18 Receptor Accessory Protein 3′UTR in Amyotrophic Lateral Sclerosis.

    Chen Eitan, Aviad Siany, Elad Barkan, Tsviya Olender, Kristel R. van Eijk, Matthieu Moisse, Sali M. K. Farhan, Yehuda M. Danino, Eran Yanowski, Hagai Marmor-Kollet, Natalia Rivkin, Nancy Yacovzada, Shu-Ting Hung, Johnathan Cooper-Knock, Chien-Hsiung Yu, Cynthia Louis, Seth L. Masters, Kevin P. Kenna, Rick A. A. van der Spek, William Sproviero, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Ashley R. Jones, Yael Elbaz Alon, Yahel Cohen, Elik Chapnik, Daphna Rothschild, Omer Weissbrod, Gilad Beck, Elena Ainbinder, Shifra Ben-Dor, Sebastian Werneburg, Dorothy P. Schafer, Robert H. Brown Jr, Pamela J. Shaw, Philip Van Damme, Leonard H. van den Berg, Hemali P. Phatnani, Eran Segal, Justin K. Ichida, Ammar Al-Chalabi, Jan H. Veldink, Project MinE ALS Sequencing Consortium, NYGC ALS Consortium, Eran Hornstein
    Phatnani Lab Biology, Genomics & Technology Neurodegenerative Disease
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  • bioRxiv  ·  January 12, 2022  ·  Preprint

    Epigenetic dysregulation from chromosomal transit in micronuclei.

    Albert Agustinus, Ramya Raviram, Bhargavi Dameracharla, Jens Luebeck, Stephanie Stransky, Lorenzo Scipioni, Robert Myers Melody DiBona, Mercedes Duran, Britta Weigelt, Shira Yomtoubian, Eleonore Toufektchan, Paul Mischel, Vivek Mittal, Sohrab Shah, John Maciejowski, Enrico Gratton, Peter Ly, Mathieu Bakhoum, Dan Landau, Vineet Bafna, Simone Sidoli, Yael David, Samuel F Bakhoum

    Landau Lab Cancer Biology, Genomics & Technology
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