Sanjana Lab
Neville Sanjana’s lab develops technologies to understand how human genetic variants cause disease, with applications to the immune system, nervous system and cancer. The lab employs a multi-disciplinary approach, combining genome engineering, pooled genetic screens and massively-parallel DNA synthesis, bioinformatics, single-cell multiomics, and imaging, to dissect the inner workings of the human genome and its dysfunction in autism, autoimmunity and tumor evolution. The Sanjana lab is a team of molecular engineers, biologists, immunologists, neuroscientists, computer scientists and bioscience entrepreneurs who are passionate about creating new technologies for genomics and advancing human health. The lab is also affiliated with the Department of Biology at New York University.
Neville Sanjana, PhD
Core Faculty Member, NYGC
Associate Professor of Biology, Neuroscience and Physiology, NYU
Latest News & Publications
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European Journal of Immunology · February 25, 2026
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bioRxiv · February 20, 2026 · Preprint
Rational design of synthetic proteins using a genome-scale CRISPR screen.
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bioRxiv · February 11, 2026 · Preprint
Identification of target genes and regulatory networks for bone mineral density GWAS loci through systematic targeting and inhibition.
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