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Science & Technology > Faculty Labs > Lappalainen Lab

Lappalainen Lab

Tuuli Lappalainen’s lab studies functional genetic variation in human populations. It is particularly interested in regulatory variation affecting the transcriptome, as well as cellular mechanisms underlying genetic associations to disease. The lab integrates computational analysis of genomic and transcriptomic data with population genetic and experimental analysis.

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Tuuli Lappalainen, PhD

Senior Associate Faculty Member, NYGC
Director, National Genomics Infrastructure, SciLifeLab; Professor, KTH School of Engineering Sciences in Chemistry, Biotechnology and Health; Former Assistant Professor, Department of Systems Biology, Columbia University

About Dr. Lappalainen

Latest News & Publications

bioRxiv · August 7, 2025 · Preprint

Non-linear transcriptional responses to gradual modulation of transcription factor dosage.

Lappalainen Lab Sanjana Lab Technology Innovation
Atherosclerosis · May 20, 2025

Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease.

Lappalainen Lab
biorXiv · May 5, 2025 · Preprint

CRISPRi perturbation screens and eQTLs provide complementary and distinct insights into GWAS target genes.

Sanjana Lab Lappalainen Lab

July 9, 2024
Tuuli Lappalainen, PhD, Selected As Member of EMBO

Lappalainen Lab Biology, Genomics & Technology Population Genomics

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