Our Scientific Publications
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Nature Biotechnology · March 16, 2020
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bioRxiv · February 24, 2020 · Preprint
An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation.
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Cell Reports · March 3, 2020
High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation.
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bioRxiv · February 11, 2020 · Preprint
Recent Ultra-rare Inherited Mutations Identify Novel Autism Candidate Risk Genes
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Nature · February 6, 2020
The evolutionary history of 2,658 cancers.
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Nature · February 5, 2020
Pan-cancer analysis of whole genomes.
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Neurochem Res. · February 4, 2020
Dynamic Lamin B1-Gene Association During Oligodendrocyte Progenitor Differentiation.
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Genome Biology · December 23, 2019
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression.
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Science Translational Medicine · December 18, 2019
Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology.
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Scientific Reports · December 13, 2019
Deep sequencing of 3 cancer cell lines on 2 sequencing platforms
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PLoS Genet · December 13, 2019
Leveraging allelic imbalance to refine fine-mapping for eQTL studies.
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Cell · December 12, 2019
Toward a Common Coordinate Framework for the Human Body.
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Nature Neuroscience · November 25, 2019
Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.
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Genome Biology · November 21, 2019
EpiMethylTag simultaneously detects ATAC-seq or ChIP-seq signals with DNA methylation.
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PNAS · November 20, 2019
Effects of ALS-associated TANK binding kinase 1 mutations on protein–protein interactions and kinase activity
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bioRxiv · November 18, 2019 · Preprint
Genome-wide profiling of druggable active tumor defense mechanisms to enhance cancer immunotherapy
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Journal of Heredity · November 14, 2019
Adaptive Radiation Genomics of Two Ecologically Divergent Hawai‘ian Honeycreepers: The ‘akiapōlā‘au and the Hawai‘i ‘amakihi.
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Molecular Biology and Evolution · November 8, 2019
Phylogenomics identifies an ancestral burst of gene duplications predating the diversification of aphidomorpha.
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bioRxiv · November 7, 2019 · Preprint
Nanopore sequencing of DNA concatemers reveals higher-order features of chromatin structure
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Genome Biology · November 4, 2019
Genetic regulation of gene expression and splicing during a 10-year period of human aging.
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Pigment Cell & Melanoma Research · November 2, 2019
Sequencing two Tyr::CreERT2 transgenic mouse lines.