Our Scientific Publications
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Cell Stem Cell · April 7, 2022
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Nature Neuroscience · March 31, 2022
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3′UTR protect against ALS.
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Nature Communications · March 28, 2022
Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.
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Scientific Reports · March 24, 2022
An open source toolkit for repurposing Illumina sequencing systems as versatile fluidics and imaging platforms.
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Nature Biotechnology · March 24, 2022
Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro
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bioRxiv · March 18, 2022 · Preprint
Integrated protein and transcriptome high-throughput spatial profiling.
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Nature · March 16, 2022
A genome-scale screen for synthetic drivers of T cell proliferation.
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Cell Reports · March 15, 2022
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
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Cell Genomics · March 9, 2022
Single nucleus multi-omics identifies human cortical cell regulatory genome diversity.
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bioRxiv · March 8, 2022 · Preprint
Nanobody-tethered transposition allows for multifactorial chromatin profiling at single-cell resolution.
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bioRxiv · February 24, 2022 · Preprint
Dictionary learning for integrative, multimodal, and scalable single-cell analysis.
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Blood · February 24, 2022
A BAX door to venetoclax resistance.
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Nature · February 23, 2022
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.
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Nature Reviews Cancer · February 22, 2022
CRISPR in cancer biology and therapy.
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Cell Reports Medicine · February 15, 2022
System-wide transcriptome damage and tissue identity loss in COVID-19 patients.
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Nature Communications · February 11, 2022
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium.
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Nature Biotechnology · February 7, 2022
Curated variation benchmarks for challenging medically relevant autosomal genes.
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bioRxiv · February 2, 2022 · Preprint
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq.
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PLoS Genet · January 31, 2022
Transcription factor regulation of eQTL activity across individuals and tissues.
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bioRxiv · January 20, 2022 · Preprint
Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring.
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Genome Biology · January 18, 2022
Comparison and evaluation of statistical error models for scRNA-seq.