Our Scientific Publications
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Trends Cancer · March 26, 2026
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Brief Bioinform · March 27, 2026
Comparison of variant callers using 60 532 multi-ancestry whole genome sequences.
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medRxiv · March 23, 2026 · Preprint
A scalable and equitable framework for target and patient prioritisation in rare disease antisense therapeutics.
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bioRxiv · March 27, 2026 · Preprint
Systematic identification of seed-driven off-target effects in Perturb-seq experiments.
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bioRxiv · March 26, 2026 · Preprint
Mutant p53 Directs PARP to Regulate Replication Stress and Drive Breast Cancer Metastasis.
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Nature Communications · March 25, 2026
CRISPR tiling deletion screens reveal functional enhancers and allelic compensation effects (ACE) on SIN3A transcription.
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Trends Genet . · March 23, 2026
GRIN2A: one gene, many phenotypes.
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Cell · March 19, 2026
Human-specific features of the cerebellum and ZP2-regulated synapse development.
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Nature Genetics · March 19, 2026
A meta-analysis of single-nucleus expression quantitative trait loci linking genetic risk to brain disorders.
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bioRxiv · March 18, 2026 · Preprint
Genome-scale functional mapping of the mammalian whole brain with in vivo Perturb-seq.
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bioRxiv · March 13, 2026 · Preprint
An explainable boosting machine model for identifying artifacts caused by formalin-fixed paraffin embedding.
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Cell Report · March 12, 2026
Single-cell epigenomics uncovers heterochromatin instability and transcription factor dysfunction during mouse brain aging.
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Cell · March 11, 2026
Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain.
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Mol Cell. · March 4, 2026
Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes.
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Proc Natl Acad Sci U S A. · March 10, 2026
Loss of function of the chromatin remodeling gene INO80D leads to neurogenic features of schizophrenia.
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Neurodev Disord · March 7, 2026
Crossing the finish line towards a disease-modifying treatment for Angelman syndrome.
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bioRxiv · March 7, 2026 · Preprint
Single-molecule spatial genomics reveals the multi-scale organization and plasticity of extrachromosomal DNA in glioblastoma.
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Genome Research · March 4, 2026 · Preprint
Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson’s disease.
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Genome Biology · February 28, 2026
Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia.
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European Journal of Immunology · February 25, 2026
Curbing Autoimmunity: A New Fab Fragment Targeting CD40-CD40L Halts B-Cell Activation and Differentiation.
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Translational Psychiatry · February 24, 2026
In-Depth characterization of the shared genetic architecture of suicide attempts with other major psychiatric disorders.