Publications

43
Results
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Science. 2023 May 19.
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
Science. 2023 May 4.
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
Nature Methods 2022 Dec. 22.
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq.
ACS Synthetic Biology. 2022 Nov. 15.
Expanding the Scope of Bacterial CRISPR Activation with PAM-Flexible dCas9 Variants.
Methods in Molecular Biology. 2022 Sept. 11.
Ligand Identification for Orphan MHC-Agnostic T-Cell Receptors by Whole Genome CRISPR–Cas9 Screening.
Nature Communications. 2022 Aug. 5.
Recurrent somatic mutations as predictors of immunotherapy response.
Cell Reports. 2022 Aug. 02.
Cancer genes disfavoring T cell immunity identified via integrated systems approach.
Nature. 2022 March 16.
A genome-scale screen for synthetic drivers of T cell proliferation.
Cell Reports. 2022 March 15.
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
Nature Reviews Cancer. 2022 Feb. 22.
CRISPR in cancer biology and therapy.
iScience. 2021 Oct. 29.
Automated design of CRISPR prime editors for thousands of human pathogenic variants.
Cell Genomics. 2021 Sept. 3.
Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens.
Genome Biology. 2021 Aug. 23.
Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus.
Nature Reviews Molecular Cell Biology. 2021 Aug. 11.
Voices of the new generation: open science is good for science (and for you).
Cell Chemical Biology. 2021 Aug 2.
Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells.
Nature Biotechnology. 2021 May 19.
Tracking cell lineages to improve research reproducibility.
Nature Biotechnology 2021 Apr. 29.
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens.
Genome Biology. 2021 Mar. 4.