Our Scientific Publications
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bioRxiv · December 2, 2025 · Preprint
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medRxiv · December 3, 2025 · Preprint
Machine Learning-Based Prediction of Cell-type Resolved Brain eQTLs Enhances Discovery of Variants Explainin.g Alzheimer’s Disease Heritability
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Cancer Discovery · December 6, 2025
Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia.
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HGG Adv . · December 4, 2025
Epigenome-wide association study meta-analysis of BMI in African Americans
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Nucleic Acids Research · December 3, 2025
FAVOR 2.0: A reengineered functional annotation of variants online resource for interpreting genomic variation.
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Stem Cells and Development · December 3, 2025
The Specification and Functional Maturation of Sub-Cerebral Projection Neurons Derived from Human Induced Pluripotent Stem Cells.
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medRxiv · December 2, 2025 · Preprint
Sex-Specific Genetic Architecture and Comorbidities of Alcohol Use Behaviors.
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Nature Communications · December 2, 2025
Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy.
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bioRxiv · December 1, 2025 · Preprint
Robust Integration of Sparse Single-Cell Alternative Splicing and Gene Expression Data with SpliceVI.
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Molecular Psychiatry · November 28, 2025
3D genetic architecture of schizophrenia risk across three neuronal subtypes.
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Npj Breast Cancer · November 27, 2025
Functional and clinical significance of the RNA m6A methyltransferase complex in breast cancer.
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Nature Genetics · November 27, 2025
Passenger mutations link cellular origin and transcriptional identity in human lung adenocarcinomas.
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Molecular Psychiatry · November 25, 2025
Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health.
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bioRxiv · November 25, 2025 · Preprint
Transcriptome-wide profiling of alternative splicing regulators with CRISPore-seq.
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Nature Methods · November 24, 2025
From slices to deep dishes: spatial transcriptomics and translatomics of thick tissue blocks.
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medRxiv · November 22, 2025 · Preprint
Biobank-scale Bayesian TWAS reveals splicing-mediated mechanisms of complex disease.
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medRxiv · November 19, 2025 · Preprint
Common and rare variant genetic contributions in African Americans with autism.
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bioRxiv · November 10, 2025 · Preprint
Disruption of Cell-Type-Specific Molecular Programs of Medium Spiny Neurons in Autism.
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Nature Biomedical Engineering · November 9, 2025
Neuroimaging endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders.
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bioRxiv · November 5, 2025 · Preprint
Distinct patterns of de novo coding variants contribute to Tourette Syndrome etiology.
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bioRxiv · November 5, 2025 · Preprint
Large-scale discovery of neural enhancers for cis-regulation therapies.