Our Scientific Publications
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JAMA Network Open · January 15, 2026
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Genome Biology · January 15, 2026
Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants.
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Nature · January 14, 2026
Microbiota-induced T cell plasticity enables immune-mediated tumour control.
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eLife · January 14, 2026
Nonlinear transcriptional responses to gradual modulation of transcription factor dosage.
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American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · January 13, 2026
Are There Causal Associations Between Obsessive-Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi-Directional Mendelian Randomization Study.
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bioRxiv · January 9, 2026 · Preprint
TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues.
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Cancer Cell · January 12, 2026
Characterization of a pathogenic subpopulation of human glioma associated macrophages linked to glioma progression.
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American Society for Microbiology · January 8, 2026
Case-control and genomic epidemiology characterization of SARS-CoV-2 breakthrough infections during the Delta-to-Omicron transition.
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Nature Biotechnology · January 5, 2026
Mapping isoforms and regulatory mechanisms from spatial transcriptomics data with SPLISOSM.
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Cancer Discovery · December 31, 2025
Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts.
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bioRxiv · December 30, 2025 · Preprint
Aging-associated alternative splicing programs conserved between human and mouse tissues.
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Nature Cell Biology · December 29, 2025
T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response.
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bioRxiv · December 26, 2025 · Preprint
UC Irvine Brain Initiative Cell Atlas Network (BICAN) Brain Procurement Program for the Center for Multiomic Human Brain Cell Atlas Project.
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Signal Transduction and Targeted Therapy · December 25, 2025
Inhibition of RNA-binding proteins enhances immunotherapy in ovarian cancer.
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bioRxiv · December 25, 2025 · Preprint
A Retinoic Acid Autoregulatory Loop Governing Prefrontal-Motor Arealization.
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Alzheimer's & Dementia · December 24, 2025
Sex-specific patterns of a machine learning-derived Alzheimer’s brain atrophy imaging signature in participants without diagnosed cognitive impairment: A multi-cohort study.
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bioRxiv · December 20, 2025 · Preprint
Aging-induced hepatocyte CD44 drives IL6/STAT3 signaling and associates with impaired neighboring T cell function.
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J Gerontol A Biol Sci Med Sci. · December 22, 2025
The Sixth Annual Symposium of the Midwest Aging Consortium.
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bioRxiv · December 18, 2025 · Preprint
Wavelet Based Whole Genome Doubling Aware Single Cell Copy Number Calling.
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Eur Heart J · December 22, 2025
LIPA, a risk locus for coronary artery disease: decoding the variant-to-function relationship.
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Nat Commun . · December 20, 2025
Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D