Publications

40
Results
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Cell Stem Cell. 2023 Aug. 14.
Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths.
Nature. 2023 June 7.
Epigenetic dysregulation from chromosomal transit in micronuclei.
Nature Biotechnology. 2023 Jan. 2.
Integration of whole transcriptome spatial profiling with protein markers.
Nature Biotechnology. 2022 Dec. 19.
Nanobody-tethered transposition enables multifactorial chromatin profiling at single-cell resolution.
Nature Genetics. 2022 Sept. 22.
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
Cell Stem Cell. 2022 Apr. 7.
Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction.
Blood. 2022 Feb. 24
A BAX door to venetoclax resistance.
Nature. 2021 Dec. 8.
A heritable, non-genetic road to cancer evolution.
Med. 2021 Oct. 8.
Lightning does strike twice: leveraging phased variants to enhance minimal residual disease detection.
Annals of the New York Academy of Sciences. 2021 Oct. 3.
Single cell biology-a Keystone Symposia report.
Nature Genetics. 2021 Sept. 30.
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.
Nature Communications. 2021 Sept. 13.
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Nature Protocols 2021 July 9.
Smart-RRBS for single-cell methylome and transcriptome analysis.
Molecular Cell. 2021 May 20.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Nature Reviews Genetics. 2020 August 17.
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics.
Cell Reports. 2020 June 23.
Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus.
Cell Reports. 2020 Jun 2.
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells.
Nature Medicine. 2020 Jun 1.