Publications

13
Results
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Nature Biotechnology. 2023 July 3.
Prediction of on-target and off-target activity of CRISPR-Cas13d guide RNAs using deep learning.
Bioinformatics. 2023 Feb. 16.
LDmat: Efficiently Queryable Compression of Linkage Disequilibrium Matrices.
PLOS Genetics. 2023 Jan. 19.
Using epigenomics to understand cellular responses to environmental influences in diseases.
Nature Neuroscience. 2022 Dec. 8.
Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes.
PLOS Computational Biology. 2022 Oct. 20.
Deep mendelian randomization: Investigating the causal knowledge of genomic deep learning models.
American Journal of Human Genetics. 2021 Dec. 2.
Welch-weighted Egger regression reduces false positives due to correlated pleiotropy in Mendelian randomization.
American Journal of Human Genetics. 2021 Sept. 27.
An integrated approach to identify environmental modulators of genetic risk factors for complex traits.
Cell. 2020 October 1.
Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.
Genome Biology. 2019 Nov. 4.
Genetic regulation of gene expression and splicing during a 10-year period of human aging.
Nat Genet. 2019 2019 Mar 29.
Opportunities and challenges for transcriptome-wide association studies.
Nature Genetics. 2017 December 11.
Annotation-free quantification of RNA splicing using LeafCutter.
Nature Methods. 2017 May 22.
Allele-specific expression reveals interactions between genetic variation and environment.
Elife. 2018 May 8.