Publication Archives - Page 29 of 68 - New York Genome Center

Cell Genomics · September 3, 2021

Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens.

Xinyi Guo, Hans-Hermann Wessels, Alejandro Méndez-Mancilla, Daniel Haro, Neville E. Sanjana

Biology, Genomics & Technology

Technology Innovation

Communications Biology · September 1, 2021

Rates of contributory de novo mutation in high and low-risk autism families.

Yoon S, Munoz A, Yamrom B, Lee YH, Andrews P, Marks S, Wang Z, Reeves C, Winterkorn L, Krieger AM, Buja A, Pradhan K, Ronemus M, Baldwin KK, Levy D, Wigler M, Iossifov I

Iossifov Lab

Biology, Genomics & Technology

Neuropsychiatric Disease

Computational Biology Lab

Nature Reviews Methods Primers · August 26, 2021

Genome-wide association studies.

Emil Uffelmann, Qin Qin Huang, Nchangwi Syntia Munung, Jantina de Vries, Yukinori Okada, Alicia R. Martin, Hilary C. Martin, Tuuli Lappalainen & Danielle Posthuma

Lappalainen Lab

Biology, Genomics & Technology

Computational Biology Lab

Technology Innovation

mSphere · August 25, 2021

Emergence of multiple SARS-CoV-2 antibody escape variants in an immunocompromised host undergoing convalescent plasma treatment.

Liang Chen, Michael C. Zody, Clara Di Germanio, Rachel Martinelli, Jose R. Mediavilla, Marcus H. Cunningham, Kaelea Composto, Kar Fai Chow, Milena Kordalewska, André Corvelo, Dayna M. Oschwald, Samantha Fennessey, Marygrace Zetkulic, Sophia Dar, Yael Kramer, Barun Mathema, Soren Germer, Mars Stone, Graham Simmons, Michael P. Busch, Tom Maniatis, David S. Perlin, and Barry N. Kreiswirth

Maniatis Lab

Biology, Genomics & Technology

Computational Biology Lab

Genome Biology · August 23, 2021

Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus.

, Zharko Daniloski, , Benjamin R. tenOever, Neville E. Sanjana, Tuuli Lappalainen

Lappalainen Lab Sanjana Lab

Biology, Genomics & Technology

Technology Innovation

Hum Mol Genet · August 20, 2021

Epigenome-wide association study of mitochondrial genome copy number.

Wang P, Castellani CA, Yao J, Huan T, Bielak LF, Zhao W, Haessler J, Roby J, Sun X, Guo X, Longchamps RJ, Manson JE, Grove ML, Bressler J, Taylor KD, Lappalainen T, Kasela S, Van Den Berg DJ, Hou L, Reiner A, Liu Y, Boerwinkle E, Smith JA, Peyser PA, Fornage M, Rich SS, Rotter JI, Kooperberg C, Arking DE, Levy D, Liu C; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium..

Lappalainen Lab

Biology, Genomics & Technology

Computational Biology Lab

Technology Innovation

npg Genomic Medicine · August 16, 2021

Multiregional genetic evolution of metastatic uveal melanoma.

Rodriguez DA, Yang J, Durante MA, Shoushtari AN, Moschos SJ, Wrzeszczynski KO, Harbour JW, Carvajal RD.

Cancer Clinical Genetics

Nature Reviews Molecular Cell Biology · August 11, 2021

Voices of the new generation: open science is good for science (and for you).

Sanjana NE.

Sanjana Lab

Cancer

Computational Biology Lab

Technology Innovation

Cold Spring Harb Mol Case Stud · August 6, 2021

Metastatic Pediatric Sclerosing Epithelioid Fibrosarcoma.

Woods AD, Purohit R, Mitchell L, Collier J, Collier K, Lathara M, Learned K, Vaske O, Geiger H, Wrzeszczynski KO, Jobanputra V, Srinivasa G, Rudzinski E, Whelan K, Beierle E, Spunt S, Keller C, Wadhwa A.

Cancer

Biology, Genomics & Technology

Computational Biology Lab Clinical Genetics

Cell Chemical Biology · August 2, 2021

Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells.

Alejandro Méndez-Mancilla, Hans-Hermann Wessels, Mateusz Legut, Anastasia Kadina, Megumi Mabuchi, John Walker, G. Brett Robb, Kevin Holden, Neville E Sanjana

Sanjana Lab

Biology, Genomics & Technology

Computational Biology Lab