Publication > Page 18
  • Cell Reports Methods  ·  March 12, 2025

    A sequence context-based approach for classifying tumor structural variants without paired normal samples.

    Wolu Chukwu, Siyun Lee, Alexander Crane, Shu Zhang, Sophie Webster, Oumayma Dakhama, Ipsa Mittra, Carlos Rauert, Marcin Imielinski, Rameen Beroukhim, Frank Dubois, Simona Dalin

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  • Cell Reports  ·  March 10, 2025

    ALS molecular subtypes are a combination of cellular and pathological features learned by deep multiomics classifiers.

    Kathryn O’Neill, Regina Shaw, Isobel Bolger, NYGC ALS Consortium, Oliver H. Tam, Hemali Phatnani, Molly Gale Hammell

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  • Nature Communications  ·  March 10, 2025

    Secure and scalable gene expression quantification with pQuant.

    Seungwan Hong, Conor R. Walker, Yoolim A. Choi & Gamze Gürsoy

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  • Nature Genetics  ·  March 7, 2025

    Comparison of the multivariate genetic architecture of eight major psychiatric disorders across sex.

    Ted Schwaba, Travis T. Mallard, Adam X. Maihofer, Mijke Rhemtulla, Phil H. Lee, Jordan W. Smoller, Lea K. Davis, Michel G. Nivard, Andrew D. Grotzinger & Elliot M. Tucker-Drob

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  • Nature Genetics  ·  March 6, 2025

    Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.

    Seung Hoan Choi, Sean J. Jurgens, Ling Xiao, Matthew C. Hill, Christopher M. Haggerty, Garðar Sveinbjörnsson, Valerie N. Morrill, Nicholas A. Marston, Lu-Chen Weng, James P. Pirruccello, David O. Arnar, Daniel Fannar Gudbjartsson, Helene Mantineo, Aenne S. von Falkenhausen, Andrea Natale, Arnljot Tveit, Bastiaan Geelhoed, Carolina Roselli, David R. Van Wagoner, Dawood Darbar, Doreen Haase, Elsayed Z. Soliman, Giovanni E. Davogustto, Goo Jun, Hugh Calkins, Jeffrey L. Anderson, Jennifer A. Brody, Jennifer L. Halford, John Barnard, John E. Hokanson, Jonathan D. Smith, Joshua C. Bis, Kendra Young, Linda S. B. Johnson, Lorenz Risch, Lorne J. Gula, Lydia Coulter Kwee, Mark D. Chaffin, Michael Kühne, Michael Preuss, Namrata Gupta, Navid A. Nafissi, Nicholas L. Smith, Peter M. Nilsson, Pim van der Harst, Quinn S. Wells, Renae L. Judy, Renate B. Schnabel, Renee Johnson, Roelof A. J. Smit, Stacey Gabriel, Stacey Knight, Tetsushi Furukawa, Thomas W. Blackwell, Victor Nauffal, Xin Wang, Yuan-I Min, Zachary T. Yoneda, Zachary W. M. Laksman, Connie R. Bezzina, Alvaro Alonso, Bruce M. Psaty, Christine M. Albert, Dan E. Arking, Dan M. Roden, Daniel I. Chasman, Daniel J. Rader, David Conen, David D. McManus, Diane Fatkin, Emelia J. Benjamin, Eric Boerwinkle, Gregory M. Marcus, Ingrid E. Christophersen, J. Gustav Smith, Jason D. Roberts, Laura M. Raffield, M. Benjamin Shoemaker, Michael H. Cho, Michael J. Cutler, Michiel Rienstra, Mina K. Chung, Morten S. Olesen, Moritz F. Sinner, Nona Sotoodehnia, Paulus Kirchhof, Ruth J. F. Loos, Saman Nazarian, Sanghamitra Mohanty, Scott M. Damrauer, Stefan Kaab, Susan R. Heckbert, Susan Redline, Svati H. Shah, Toshihiro Tanaka, Yusuke Ebana, Regeneron Genetics Center, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Hilma Holm, Kari Stefansson, Christian T. Ruff, Marc S. Sabatine, Kathryn L. Lunetta, Steven A. Lubitz & Patrick T. Ellinor

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  • Nature Cell Biology  ·  February 26, 2025

    Systematic reconstruction of molecular pathway signatures using scalable single-cell perturbation screens.

    Longda Jiang, Carol Dalgarno, Efthymia Papalexi, Isabella Mascio, Hans-Hermann Wessels, Huiyoung Yun, Nika Iremadze, Gila Lithwick-Yanai, Doron Lipson & Rahul Satija

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  • PLOS Biology  ·  February 21, 2025

    Caspase 3 and caspase 7 promote cytoprotective autophagy and the DNA damage response during non-lethal stress conditions in human breast cancer cells.

    Gayathri Samarasekera, Nancy E. Go, Courtney Choutka, Jing Xu,Yuka Takemon, Jennifer Chan, Michelle Chan, Shivani Perera, Samuel Aparicio, Gregg B. Morin, Marco A. Marra, Suganthi Chittaranjan, Sharon M. Gorski

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  • eLife  ·  February 20, 2025

    Systems genomics of salinity stress response in rice.

    Sonal Gupta, Simon Niels Groen, Maricris L Zaidem, Andres Godwin C Sajise, Irina Calic, Mignon Natividad, Kenneth McNally, Georgina V Vergara, Rahul Satija, Steven J Franks, Rakesh K Singh, Zoé Joly-Lopez, Michael D Purugganan

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  • Nature Genetics  ·  February 17, 2025

    Multiomic single-cell profiling identifies critical regulators of postnatal brain.

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