Very Rare Cancer Consortium Disease Spotlight & Research Roundtable
Please join us for the Very Rare Cancer Consortium Tumor Board Meeting. This new initiative aims to bring cancer researchers across New York to the table to discuss compelling rare cancer cases presented by physicians and scientists from the New York Genome Center’s partner institutions. Click here to learn more about the Very Rare Cancer Consortium.
WHEN:
Thursday, March 18, 2021
4pm – 6pm
DESMOPLASTIC SMALL ROUND CELL TUMOR (DSRCT)
Disease Spotlight & Research Roundtable
This will be a VIRTUAL meeting via Zoom.
Please note registration is required.
Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive cancer occurring predominantly in adolescents and young adults. Although DSRCT’s characteristic translocation between the EWSR1 and WT1 genes has been well described, the disease overall remains poorly understood and overall survival for patients with DSRCT remains unacceptably low. Given the rarity of the disease, no randomized trials have been performed and pre-clinical tools in which to study the disease remain limited, making collaborative efforts essential. We will hear from experts about the current understanding of DSRCT, review the many areas in which this understanding could be deepened, and discuss potential collaborations through the VRCC.
SPEAKERS AND AGENDA
Introduction to the Disease
 |
Emily Slotkin, MD Pediatric Sarcoma Service, MSK KIDS Memorial Sloan Kettering Cancer Center |
Genomic and Molecular Landscape
 |
Marc Ladanyi, MD Attending Pathologist and Chief, Molecular Diagnostics Service Member, Human Oncology & Pathogenesis Program Memorial Sloan Kettering Cancer Center Affiliate Member New York Genome Center |
Causes and Function of Chromosomal
Translocations in DSRCT
 |
Alex Kentsis, MD, PhD Director, Tow Center for Developmental Oncology, Sloan Kettering Institute and Department of Pediatrics, MSK Kids Memorial Sloan Kettering Cancer Center Departments of Pediatrics, Pharmacology, and Physiology & Biophysics, Weill Medical College of Cornell University |
Transcriptomics and Unique Bioinformation
Approaches in DSRCT
 |
Andrea Califano, PhD Clyde and Helen Wu Professor of Chemical and Systems Biology Founding Chair, Department of Systems Biology Director, JP Sulzberger Columbia Genome Center Associate Director for Bioinformatics, Herbert Irving Comprehensive Cancer Center Columbia University Irving Medical Center Affiliate Member New York Genome Center |
 |
Prabhjot S. Mundi, MD Department of Medicine Division of Hematology/Oncology Columbia University Irving Medical Center |
Review of Investigational Therapeutic Approaches
 |
Emily Slotkin, MD Pediatric Sarcoma Service, MSK KIDS Memorial Sloan Kettering Cancer Center |
 |
Marc Ladanyi, MD Attending Pathologist and Chief, Molecular Diagnostics Service Member, Human Oncology & Pathogenesis Program Memorial Sloan Kettering Cancer Center Affiliate Member New York Genome Center |
 |
Madelyn Espinosa-Cotton, PhD
|
 |
Lauren Banks, MD, PhD
|
 |
Joseph A. Ludwig, MD Associate Professor Department.of Sarcoma Medical Oncology, Division of Cancer Medicine University of Texas MD Anderson Cancer Center |
Discussion
Any questions on this event, contact events@nygenome.org.