Whole Genome and Transcriptome Sequencing (WGTS) for Oncology
Whole genome sequencing (WGTS) for oncology is a complex genetic test which involves sequencing the genome of the tumor and the matched normal specimen and transcriptome sequencing of the tumor specimen. In comparison to whole exome sequencing (WES), this test includes sequencing both the protein coding regions of the genome (exons) and the non-protein coding regions of the genome (introns). This test is indicated for cancer (solid tumors or hematological malignancies) where a mutational profile from multiple genes would be informative for disease stratification, prognosis, or treatment options or alternative treatments, including targeted therapies and eligibility for clinical trials.
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