As the cost of next-generation genome sequencing has gone down, broad studies of genomics across large populations have become not only feasible but a necessity if we are to realize the promise of this revolutionary technology. In a few short years, the NYGC has built a state-of-the-art facility and innovated in areas like bioinformatics, data storage and analysis, becoming a major player in this rapidly evolving field.  NYGC is well-positioned to provide the infrastructure and expertise for these large-scale, whole genome sequencing activities.

NYGC Core Faculty Member Tuuli Lappalainen, PhD, has pioneered the integration of large-scale genome and transcriptome sequencing data to understand how genetic variation affects gene expression, providing insight to cellular mechanisms underlying genetic risk for disease. The work of her research group at NYGC links computational and population genomics to experimental molecular biology.

NYGC Population Genomics Group
The NYGC has created a Population Genomics Group that brings together leading population and statistical geneticists and focuses on human population genomics, statistical analyses, and applications to precision medicine. The group is led by Eimear Kenny, PhD, of the Icahn School of Medicine at Mount Sinai, and Adam Siepel, PhD, of Cold Spring Harbor Laboratory.

Recent Accomplishments:

New Study Explains Why Genetic Mutations Cause Disease in Some People but Not in Others

The Mark Foundation for Cancer Research Awards  a $1M grant to the New York Genome Center (NYGC) to Support the Polyethnic-1000 Project

NYGC Is Partner on Genomic Study for Children Underrepresented in Research