Blog Archives

Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.

Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq.

Expanding the Scope of Bacterial CRISPR Activation with PAM-Flexible dCas9 Variants.

Ligand Identification for Orphan MHC-Agnostic T-Cell Receptors by Whole Genome CRISPR–Cas9 Screening.

Genome-wide CRISPR/Cas9 Screens Reveal Shared and Bespoke Mechanisms of Resistance to SHP2 inhibition.

Recurrent somatic mutations as predictors of immunotherapy response.