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November
2019
7
Teresa Venezia Bowman, PhD

4:00 PM — 6:00 PM

Albert Einstein College of Medicine

See New York Genome Center’s lecture series, events and archives VIEW FULL CALENDAR

About

Teresa Venezia Bowman, PhD

Associate Professor
Department of Developmental and Molecular Biology
Department of Medicine (Oncology)
Gottesman Institute of Stem Cell Biology and Regenerative Medicine
Albert Einstein College of Medicine

 

“Finding Balance: The Importance of R-loop Homeostasis in Development and Disease”

 

REGISTER

 

4-5PM: Lecture & Audience Q&A
5-6PM: Networking & Cocktail Reception

 

The Bowman laboratory focuses on understanding the role of RNA processing in cancer and development. They employ the many advantages of the zebrafish model, such as optical transparency, high fecundity, and facile genetics approaches, to determine how defects in RNA processing factors impact hematopoietic and neural development. Using genetic models, they have identified Splicing Factor 3B, subunit 1 (SF3B1) and DEAD-box Helicase 41 (DDX41) as in vivo suppressors of R-loop-mediated DNA damage involved in cancer and neurodegenerative diseases. Taking advantage of high throughput in vivo screening capabilities in zebrafish and validation studies in mammalian systems, they are taking chemical genetic approaches to find novel therapeutics that can improve the outcome for patients.

To learn more about Dr. Bowman, visit her lab page.

 

Q&A Moderator:


David A. Knowles, PhD
Core Faculty Member
New York Genome Center

Assistant Professor, Department of Computer Science
Assistant Professor, Department of Systems Biology
Columbia University

  • Workshops
  • Neurodegenerative Disease Working Group Evening Lectures
    The NYGC is leveraging the success of the Center for Genomics of Neurodegenerative Disease (CGND) to extend our work across a range of neurodegenerative diseases that have pathways in common with ALS, including Alzheimer’s, Parkinson’s and Huntington’s diseases. The NYGC has created a new Neurodegenerative Disease Working Group, led by Alison Goate, DPhil, Icahn School of Medicine at Mount Sinai, Hemali Phatnani, PhD, NYGC, and Phil De Jager, PhD, MD, MMSc, Columbia University Irving Medical Center, with the objective of bringing together researchers from NYGC’s institutional founding members, NYGC faculty, senior faculty, NYGC technology development and computational scientists, and affiliate members to discuss the underlying disease mechanisms in neurodegenerative disease.

  • Population Genomics Working Group Evening Lectures
    The NYGC has created a Population Genomics Working Group that brings together leading population and statistical geneticists and focuses on human population genomics, statistical analyses, and applications to precision medicine. The group is led by Eimear Kenny, PhD, of the Icahn School of Medicine at Mount Sinai, and Adam Siepel, PhD, of Cold Spring Harbor Laboratory.