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Jeff Leek, PhD
New York Genome Center
4:00 PM — 5:30 PM

Building a Comprehensive Resource for the Study of Human Gene Expression with Machine Learning and Data Science

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Associate Professor of Biostatistics
Johns Hopkins Bloomberg School of Public Health
“Building a Comprehensive Resource for the Study of Human Gene Expression with Machine Learning and Data Science.”
Abstract: Gene expression is an important intermediate phenotype in the study of human biology. It can be cheaply and scalably measured, is an important surrogate for protein expression, and is responsive to both inherited genetic variation and environmental exposures. Dr. Leek will discuss his efforts to build recount2 – a comprehensive database of over 70,000 gene expression samples. He will show how his lab uses cloud computing, statistical modeling, and machine learning to reproducibly unify, clean, and annotate these data. Dr. Leek will then highlight some examples of how both his lab group and others are using the resource to answer fundamental questions about human gene expression.
Biography: Jeff Leek, PhD, is an Associate Professor of Biostatistics at the Johns Hopkins Bloomberg School of Public Health and co-editor of the Simply Statistics Blog. He received his PhD in Biostatistics from the University of Washington and is recognized for his contributions to genomic data analysis and statistical methods for personalized medicine. His data analyses have helped us understand the molecular mechanisms behind brain development, stem cell self-renewal, and the immune response to major blunt force trauma. His work has appeared in the top scientific and medical journals Nature, Proceedings of the National Academy of Sciences, Genome Biology, and PLoS Medicine.
To read more about Dr. Jeff Leek’s research, please visit: Google Scholar – Jeff Leek, PhD

    The New York Genome Center’s Evening Talks events feature distinguished experts from around the world sharing genomic insights and research. They are intended to showcase and explain high science to the non-scientific community. Speakers present the latest research findings and explain its implication for helping improve clinical care for a wide array of serious diseases. The lecture is followed by a lively question-and-answer session and a post-event reception of hors d’oeuvres and cocktails. These popular free public events are held in the Center’s state-of-the-art ground-floor auditorium starting at 6:30 pm. The Evening Talks Series is sponsored by The New York Community Trust – Pyewacket Fund.

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