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Erlich Lab

Yaniv Erlich’s lab focuses on developing new strategies at the New York Genome Center in order to harness datasets from millions of people through social media and scientific resources. With that information, the lab will work to dissect the genetic architecture of complex traits to work toward bridging the missing heritability gap. Erlich’s lab consists of a group of computer scientists, statisticians, and experimentalists who are interested in integrative approaches for next generation genomics.

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    Yaniv Erlich

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    Yaniv Erlich, PhD, is a Core Member and Assistant Investigator at the New York Genome Center. He holds a joint appointment as Assistant Professor in the Computer Science Department at Columbia University.  Prior to joining NYGC, Dr. Erlich was at the Whitehead Institute at MIT. He led his own research group there as the prestigious Whitehead Fellow from 2010-2014.

    He received his PhD from the Watson School of Biological Sciences at Cold Spring Harbor Laboratory in 2010. Dr. Erlich is the recipient of the Burroughs Wellcome Career Award 2013, Harold M. Weintraub Award 2010, the IEEE/ACM-CS HPC Award 2008, and he was selected as one of 2010 Tomorrow’s PIs team of Genome Technology.

    Dr. Erlich’s research focuses on building new tools and algorithms for studying human genomics. He is developing new strategies at NYGC to harness datasets from millions of people from social media and scientific resources, and, in turn, dissect the genetic architecture of complex traits to work toward bridging the missing heritability gap. His work has been featured often in the national and international media, including the New York Times, NPR and the Wall Street Journal.

     

  • SELECTED PUBLICATIONS

    • Willems T, Zielinski, D, Gordon A, Gymrek M, Erlich Y.

      Genome-wide profiling of heritable and de novo STR variations.

      Nature Methods. 2017 Apr 24.

    • Curnin C, Gordon A, Erlich Y.

      DNA Compass: a secure, client-side site for navigating personal genetic information.

      Bioinformatics. 2017 Mar 11.

    • Erlich, Y, Zielinski, D

      DNA Fountain enables a robust and efficient storage architecture.

      Science. 2017 Mar 3.

    • Thomas Willems, Melissa Gymrek, G. David Poznik, Chris Tyler-Smith, The 1000 Genomes Project Chromosome Y Group, and Yaniv Erlich

      Population-Scale Sequencing Data Enable Precise Estimates of Y-STR Mutation Rates
    • Liu JZ, Erlich Y, Pickrell JK

      Case-control association mapping by proxy using family history of disease.

      Nat Genet. 2017 Jan 16. PMID: 28092683

    • GYMREK M, WILLEMS T, GUILMATRE A, ZENG H, MARKUS B, GEORGIEV S, DALY MJ, PRICE AL, PRITCHARD JK, SHARP AJ, ERLICH Y.

      Abundant contribution of short tandem repeats to gene expression variation in humans

      Nat Genet. 2016 Jan;48(1):22-9. doi: 10.1038/ng.3461. Epub 2015 Dec 7. (PMID 26642241)

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This work was partially supported by a gift from the Simons Foundation.