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February
2018
20
Five Points Lecture: Roel Verhaak, PhD

4:00 PM — 6:00 PM

The Jackson Laboratory for Genomic Medicine

See New York Genome Center’s lecture series, events and archives VIEW FULL CALENDAR

About

Professor

Associate Director of Computational Biology

The Jackson Laboratory for Genomic Medicine

 

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“Molecular delineation of disease progression in glioma”

 

Individual cancers are comprised of populations of genetically distinct, separated subclones that compete for resources during the disease course, leading to dynamic evolutionary processes. High throughput technologies provide a snapshot of the disease process in space and time. To better understand therapy resistance and apply precision therapeutics, a more refined understanding of glioma evolution is required that can only be provided by multi-dimensional tumor sampling. Dr. Verhaak’s lab has characterized glioma across multiple dimensions in order to delineate evolutionary patterns, to inform optimal sampling for clinical decision making, and to demonstrate that extrachromosomal DNA elements play a critical role in gliomagenesis.

 

Roel Verhaak, PhD, is a Professor and the Associate Director of Computational Biology at the Jackson Laboratory for Genomic Medicine in Farmington, CT. The Verhaak Lab focuses on mechanisms of resistance to therapy in glioma, which the group mainly interrogates through sequencing and computational biology approaches on patient samples and experimental models. The lab previously published on the genomic characterization of primary adult glioma, work that has led to revised classification of the disease followed by neuropathologists and the glioma community worldwide.

 

To learn more about Dr. Verhaak, visit his lab page and Google Scholar, Roel Verhaak, PhD.

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