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Five Points Lecture: Eli M. Van Allen, MD

4:00 PM — 6:00 PM

Harvard Medical School, Dana-Farber Cancer Institute, Brigham and Women’s Hospital and Broad Institute

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Eli M. Van Allen, MD
Assistant Professor of Medicine
Harvard Medical School


Department of Medical Oncology
Dana-Farber Cancer Institute


Department of Medicine
Brigham and Women’s Hospital


Associate Member
Broad Institute


Talk Title: “Clinical Computational Oncology for Precision Cancer Medicine


With the rapid rise of molecular profiling, integrative immunologic biomarkers, novel therapeutics, and increasingly structured medical record data, scientific strategies that link these activities through a robust data science approach may accelerate translational discoveries and transform oncology practice at the point of care.


In this presentation, Dr. Van Allen will share how an emerging interdisciplinary science at the intersection of these activities – clinical computational oncology – is leading efforts to:


1) Establish clinical interpretation algorithms that enable prospective precision oncology;
2) Discover resistance mechanisms to existing (e.g. platinum chemotherapy) and emerging (e.g. immune checkpoint blockade) cancer therapies;
3) Translate computational methods for emerging technologies into immediate clinical application, across a series of cancers and contexts.


At the intersection of clinical oncology, computational biology, and translational cancer research, clinical computational oncology will transform the wealth of data emerging at scale into discoveries that impact patients and catalytic translational research.


Eli Van Allen, MD, is an Assistant Professor of Medicine at Harvard Medical School, a clinician at Dana-Farber/Partners Cancer Care, and an Associate Member at the Broad Institute of MIT and Harvard. His research focuses on computational cancer genomics, the application of new technologies such as massively parallel sequencing to precision cancer medicine, and resistance to targeted therapeutics. As both a computational biologist and medical oncologist, he has specific expertise in clinical computational oncology and the development of algorithms to analyze and interpret genomic data for clinically focused questions. Overall, his research will make important contributions to the field of precision cancer medicine and resistance to targeted therapeutics via expertise and study in translational and clinical bioinformatics.


Originally from Los Angeles, he studied Symbolic Systems at Stanford University, obtained his MD from UCLA, and completed a residency in internal medicine at UCSF before coming to Boston and completing a medical oncology fellowship at the Dana-Farber/Partners Cancer Care program.


To learn more about Dr. Van Allen’s research, visit his lab page and Google Scholar – Eli Van Allen, MD.



Q&A Moderator:
Neville Sanjana, PhD
Core Faculty Member
New York Genome Center

Assistant Professor of Biology
New York University

Assistant Professor of Neuroscience and Physiology
NYU School of Medicine





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    The New York Genome Center’s Evening Talks events feature distinguished experts from around the world sharing genomic insights and research. They are intended to showcase and explain high science to the non-scientific community. Speakers present the latest research findings and explain its implication for helping improve clinical care for a wide array of serious diseases. The lecture is followed by a lively question-and-answer session and a post-event reception of hors d’oeuvres and cocktails. These popular free public events are held in the Center’s state-of-the-art ground-floor auditorium starting at 6:30 pm. The Evening Talks Series is sponsored by The New York Community Trust – Pyewacket Fund.

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          New York Cancer Genomics Research Network
          To advance collaborative efforts on cancer genomics, the New York Genome Center (NYGC) hosts meetings on the first Tuesday of every month to bring together leading cancer researchers, clinicians and postdocs from the NYGC’s Institutional Founding Members and other key academic institutions. The organizers include Drs. Harold Varmus (Weill Cornell Medicine & NYGC), Marcin Imielinski (Weill Cornell Medicine & NYGC), Ross Levine (Memorial Sloan Kettering Cancer Center) and Sohail Tavazoie (The Rockefeller University).