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May
2017
17
Benjamin Raphael, PhD
New York Genome Center
4:00 PM — 5:30 PM

Affiliation: Princeton University

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About

Lecture Title: Interpretation and Evolution of Cancer Genomes

 

Affiliation: Princeton University

 

Professional Title: Interpretation and Evolution of Cancer Genomes

 

Professional Title: Professor, Department of Computer Science

 

Talk Abstract: In the past few years, somatic mutations in thousands of cancer exomes/genomes have been measured by high-throughput DNA sequencing. Despite this wealth of data, our understanding of the mutational landscape in cancer remains incomplete. In this talk, Dr. Raphael will describe computational approaches to translate cancer sequencing data into deeper insights about the processes that drive cancer development. These include techniques to identify combinations of mutations that perturb cellular networks, as well as algorithms to infer patterns of tumor evolution and metastasis.

 

Biography: Benjamin Raphael, PhD, is an Associate Professor in the Department of Computer Science at Princeton University. Previous to joining Princeton University, Dr. Raphael was an Associate Professor in the Department of Computer Science and Director of the Center for Computational Molecular Biology (CCMB) at Brown University. His research focuses on the design of algorithms for genome sequencing and interpretation. Recent interests include structural variation in human and cancer genomes, and network/pathway analysis of genetic variants. Dr. Raphael received an SB in Mathematics from MIT, a PhD in Mathematics from the University of California, San Diego (UCSD), and completed postdoctoral training in Bioinformatics and Computer Science at UCSD. He is the recipient of an NSF CAREER award, a Career Award from the Burroughs Wellcome Fund and a Sloan Research Fellowship.

 

To read more about Dr. Benjamin Raphael’s research, please visit: Google Scholar – Benjamin Raphael, PhD

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    Five Points lecture series bring leading scientists from around the world for an in-depth discussion of their work with students, researchers and clinicians from the New York Genome Center, its member institutions, and others in the medical/scientific community. While Five Points lectures are free and open to the general public, these lectures are most beneficial to scientists, clinicians and researchers who wish to accelerate their research through the use of DNA sequencing technology and bioinformatics. Five Points lectures often frame five or so key points, in a nod to the series’ name — followed by 15 minutes of Q&A, and 30 minutes of networking over hors d’oeuvres and cocktails. These afternoon events are held in the Center’s state-of-the-art ground-floor auditorium starting at 4 pm.

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    EVENING TALKS
    The New York Genome Center’s Evening Talks events feature distinguished experts from around the world sharing genomic insights and research. They are intended to showcase and explain high science to the non-scientific community. Speakers present the latest research findings and explain its implication for helping improve clinical care for a wide array of serious diseases. The lecture is followed by a lively question-and-answer session and a post-event reception of hors d’oeuvres and cocktails. These popular free public events are held in the Center’s state-of-the-art ground-floor auditorium starting at 6:30 pm. The Evening Talks Series is sponsored by The New York Community Trust – Pyewacket Fund.

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