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OPPORTUNITIES

  • Academic

    Each faculty member of the NYGC leads a laboratory of post doctoral researchers, lab associates and scientific staff. They integrate their genomic expertise with the work that we are doing NYGC, working in collaborative research relationships both inside NYGC and with academic institutions. Our Faculty members hold joint appointments at our Institutional Founding Members while also managing their independent laboratories housed at the NYGC and conducting ground-breaking and collaborative genomic research.
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      Postdoctoral Researcher, Landau Lab

      Job Description

      About the New York Genome Center

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      The Landau Lab at the New York Genome Center is seeking candidates for a postdoctoral position. The Landau lab develops computational and experimental tools to study the fundamental question of somatic evolution in health and disease. Our research is geared towards uncovering basic principles in evolutionary biology, using both patient derived samples and experimental systems for modeling cancer evolution in vitro and in vivo.

      The team includes a formidable group of scientists with interest and expertise which includes technology development, mathematical modeling, computer science and deep learning approaches, single-cell technology, genome and epigenome editing, liquid biopsy, high throughput approaches for optical barcodes and immunotherapy strategies.

      In addition to the basic science interest, we also seek to apply this knowledge to designing the next generation of precision medicine tools to overcome cancer evolution, as a central challenge to cancer cure today.

      Postdoctoral researchers will have the opportunity to develop an independent research program, work with leading collaborators across NYC and the Harvard/MIT community, and receive training in cutting-edge techniques for both the dry and wet lab.

      Required Skills

      • PhD in quantitative field (i.e. statistics, physics, mathematics or computer science) with a demonstrated interest in biological questions; or
      • PhD in a biological field with strong demonstrated programming and analytical skills or technology development.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

      APPLY
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      Programmer, Erlich lab

      Job Description

      The Erlich Lab in the New York Genome Center is looking for a highly motivated individual to join our expanding lab. We need creative problem solvers with a passion for innovation to join our team and help us scale up our hybrid cloud deployment and facilitate big-data large scale genomics analysis. This individual would primarily be working on DNA.Land. https://DNA.Land is a crowdsource research project to collect genomes and traits from a large number of individuals. The project was featured in Nature, the Atlantic, and TEDxDanubia.

      The Erlich lab is part of Columbia University Computer Science Department and the NY Genome Center. Examples of the projects and work of our group can be found at http://teamerlich.org and https://github.com/teamerlich.

      Job duties will include:

      • Software development to maintain and enhance core or shared components of the website and internal pipelines and tools;
      • Unix scripting;
      • Develop, implement and maintain sysadmin solutions on both physical and cloud based servers;
      • Investigate, design and execute migration strategies to cloud based infrastructure using best practices of Amazon Web Services (AWS);
      • Address lab member’s computational needs, by deploying existing solutions, troubleshooting for user errors, or developing new tools.

      Beyond these key duties, the lab can be flexible to accommodate the interests of the individual, as there are so many possible avenues for additional projects and work. For example, this person could be focused on bioinformatics research, on machine-learning, or on programming etc. depending on their strengths and interests.

      Please include a cover letter with your application, and if you have made a public contribution to a major open source project then please explain the details in this letter.

      Position Requirements

      Required

      • BS in computer science or similar, or equivalent experience;
      • Great communication, collaboration skills and eagerness to continue learning;
      • Familiarity with Unix OS;
      • A working understanding of code and script;
      • Ability to use a wide variety of open source technologies and tools.

      Preferred

      • Comfort with frequent, incremental code testing and deployment;
      • Experience with sysadmin and IT operations;
      • Familiarity with development tools (git, make).

      The successful applicant will be part of a fast paced and dynamic team.  Our team will provide significant on-the-job training. We are looking for candidates who are smart, motivated and can take initiative. It would be a great opportunity for someone looking to gain some experience to move into industry or a PhD program in a couple of years, based on the new skillset they develop at NYGC.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
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      DevOps Engineer, Erlich lab

      Job Description

      The Erlich Lab in the New York Genome Center is looking for a highly motivated individual to join our expanding lab. We need creative problem solvers with a passion for innovation to join our team and help us scale up our hybrid cloud deployment and facilitate big-data large scale genomics analysis. This individual would primarily be working on DNA.Land. https://DNA.Land is a crowdsource research project to collect genomes and traits from a large number of individuals. The project was featured in Nature, the Atlantic, and TEDxDanubia.

      The Erlich lab is part of Columbia University Computer Science Department and the NY Genome Center. Examples of the projects and work of our group can be found at http://teamerlich.org and https://github.com/teamerlich.

      Job duties will include:

      • Software development to maintain and enhance core or shared components of the website and internal pipelines and tools;
      • Unix scripting;
      • Develop, implement and maintain sysadmin solutions on both physical and cloud based servers;
      • Investigate, design and execute migration strategies to cloud based infrastructure using best practices of Amazon Web Services (AWS);
      • Address lab member’s computational needs, by deploying existing solutions, troubleshooting for user errors, or developing new tools.

      Beyond these key duties, the lab can be flexible to accommodate the interests of the individual as there are so many possible avenues for additional projects and work. For example, this person could be focused on bioinformatics research, on machine-learning, or on programming etc. depending on their strengths and interests.

      Position Requirements

      Required

      • BS in computer science or similar + 3 years’ experience, or equivalent;
      • SQL and/or NoSQL;
      • Cloud platforms deployment (AWS strongly preferred);
      • Frontend and/or fullstack website development;
      • Demonstrated ability to produce well designed, documented code (unix shell, Python, Perl);
      • Ability to use a wide variety of open source technologies and tools;
      • Comfort with frequent, incremental code testing and deployment;
      • Experience with sysadmin and IT operations;
      • Familiarity with development tools (git, make).
      • Great communication, collaboration skills and eagerness to continue learning;
      • Knowledge of Unix OS (CentOS, Ubuntu, Mint, Debian, Fedora, etc.);

      Preferred

      • Automation/configuration management (Puppet, Chef, Ansible, etc.);
      • Setting up Continuous Integration infrastructure;
      • Cloud Monitoring tools (Nagios, Cacti, CloudWatch, Gnaglia, etc.);
      • Bioinformatics experience.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
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      Postdoctoral Associate, Sanjana Lab

      Job Description

      The Sanjana Lab at the New York Genome Center and NYU’s Department of Biology and Center for Genomics and Systems Biology is looking for an energetic and motivated individual to work as a Postdoctoral Associate within a highly creative and dynamic research team of scientists, engineers, and life science entrepreneurs.

      The Sanjana lab works at the intersection of genomics, bioengineering and neuroscience. We are curious about many things and are passionate about what we do. We primarily develop new technologies for hacking and understanding biological systems. We try to learn from nature and to re-purpose what we learn to gain deeper insights into how genomes and neural systems function. In the lab, we modify genomes, perform high-throughput screens, differentiate human neurons from stem cells, watch synapses rewire, find vulnerabilities in cancer cells and have a lot of fun in the process. We aim to have a tangible impact on improving human health by creating new biological tools and fundamental biological discovery.

      Please include the following items with your application: 1) CV with a list of publications;   2) a short summary of your present and future research interests;   3) a list of three references and their contact information.

      Required Skills

      The ideal candidate will hold a PhD or MD-PhD, have prior research experience in molecular biology, chemistry, biochemistry, neuroscience, cancer biology and/or genomics and prior peer-reviewed publications. The candidate will be expected to plan and carry out research tasks independently and write-up/present findings on a regular basis.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
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      Bioinformatics Associate, Landau Lab

      Job Description

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      The Landau Lab at the New York Genome Center is looking for a highly motivated, detail-oriented individual to join our efforts to study the basic principles of cancer evolution. As an Associate you will be trained in the analysis and interpretation of next-generation sequencing (NGS) data, originating from patient samples as well as experimental modeling of cancer evolution, under the guidance of advanced bioinformaticians.

      Job Duties:

      • Learn and assist in analyzing sequencing data using established pipelines;
      • Learn and perform appropriate QC measures;
      • Learn and develop/benchmark new tools for sequencing data analysis;
      • Assist and collaborate with internal and external researchers in interpretation of sequencing data.

      The successful applicants will be part of a fast-paced and dynamic team. The Landau Lab will provide significant on-the-job training. We seek a candidate who is motivated and can take independent initiative. This is an excellent opportunity for someone looking to gain experience to move into a PhD program within a couple of years, based on the new skillset they develop at New York Genome Center (though, this is not a requirement).

      Required Skills

      • BS or MS degree, or equivalent experience;
      • Team oriented with excellent written and verbal communication skills, collaboration skills and an eagerness to learn;
      • Exposure to NGS data analysis preferred;
      • A working understanding of code and script;
      • Training in statistics or machine learning a plus.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
  • Administration

    We believe that every team member is crucial as NYGC works towards our mission, be it in a scientific, technical, or administrative position. Our administration team plays a huge role in driving transformative change in biomedical and clinical care. This group includes external affairs, finance, legal, business development, project management, sponsored research and facilities.
    • Bioinformatics

      We are proud to boast a world-class bioinformatics and computational biology organization to support the cutting edge genomics research and integrated genomics services that we offer at NYGC. Our collaborative bioinformatics team is passionate about understanding and modeling human genetic variation and researching how it can be used to generate clinically actionable results.
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        Bioinformatics Analyst, Cancer

        Job Description

        The New York Genome Center is looking for a highly motivated, detail-oriented individual to join our expanding computational biology group. As Bioinformatics Analyst, Cancer you will be responsible for the analysis of next-generation sequencing (NGS) data. You will work as part of a team of analysts and scientists led be experienced bioinformaticians.

        Job duties will include, but are not limited to:

        • Analyze cancer sequencing data using established pipelines and workflows;
        • Perform appropriate QC measures;
        • Implement, maintain and document data analysis pipelines and workflows;
        • Benchmark new tools for cancer sequencing data analysis and propose improvements;
        • Develop and apply novel analysis approaches;
        • Assist and collaborate with internal and external researchers on analyses of NGS data;
        • Summarize results in written or oral reports for bioinformatics scientists and internal researchers;
        • Assist bioinformatics scientists in preparing text and figures for manuscripts and external presentations.

        Position Requirements

        • BS with 2+ years work/research experience in bioinformatics, computer science, biology, biochemistry or similar;
        • 1+ years demonstrated exposure to NGS data analysis; experience using standard NGS analysis software (including samtools, GATK, Picard, bedtools, etc);
        • Exposure to cancer genomics preferred; experience with somatic variant calling a plus;
        • Strong programming skills in R, Python, Perl, BASH, Java, C++ or similar;
        • Experience working in a Linux environment;
        • Experience using an SGE cluster preferred;
        • Experience working with TCGA, COSMIC, 1000 Genomes, ENCODE, or GTEx data a plus;
        • Team oriented with excellent written and verbal communication skills.

        Job Location

        New York, New York, United States

        Position Type

        Full-Time/Regular

        APPLY
    • IT and Computing

      This group develops and maintains the tools and infrastructure necessary to support our scientists as they tackle ground-breaking and large-scale data and genomic analysis. They are responsible for initiating and fostering external collaborations with technology partners, as well as ensuring that NYGC is a leader in the effective use of technology.
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        Senior Director, IT Infrastructure

        Position Description

        The Senior Director, IT Infrastructure will provide leadership for the strategic direction and oversight of NYGC’s computational, data, network and security infrastructure.

        The ideal candidate will have substantial experience developing and maintaining solutions to support large-scale, high-throughput scientific applications and data, in a 24-7, mission-critical environment.   A strong candidate will have exhaustive knowledge of the technical resources in their field, strong opinions on how best to deploy those resources, and the ability to explain his or her reasoning both at a high level and in detail. He or she must have expertise in security and understanding of security compliance issues, preferably in a HIPAA environment. The ideal candidate will also have a deep interest in using their expertise to advance medical research.

        This position will be responsible for managing multiple teams, including:

        • a research computing team that manages a multi-petabyte data storage system, multiple databases, and thousands of cores;
        • a networking and security team that is responsible for both internal and external networking (including an internal network that transfers petabytes of data per day) and security meeting high ISO and HIPAA standards, subject to regular external audits;
        • a desktop support team, responsible for deskside support of both PCs and MACs, A/V and phones;
        • a system administration team responsible for core IT functions deployed on large numbers of virtual machines.

        The Senior Director will also be responsible for developing and maintaining external collaborations with technology partners, as well as constantly evaluating emerging technologies to maintain the Center as a leader in the effective use of technology. This position will also require collaboration with IT leaders from partner institutions.

        Specific responsibilities include, but are not limited to:

        • Provide operational oversight of high-performance computing infrastructure, large-scale data storage, and possibly third-party IT services for research computing;
        • Establish metrics for service delivery to researchers;
        • Manage escalation of technical requests and continually identify opportunities for improvement in both services and architecture;
        • Directly engage the research community to understand evolving and projected requirements;
        • Manage performance of team leaders;
        • Investigate emerging technologies and services and drive innovative technology projects;
        • Understand the strengths and weaknesses of public cloud technologies and how they may be applicable in our environment;
        • Forecast capacity requirements and budgets;
        • Prepare budgets, and assist in budgeting for grant applications.

        Position Requirements

        • MS in computer science, information technology, or a computationally-intensive scientific discipline;
        • Minimum of 10 years of experience developing and deploying high-performance, high-throughput IT solutions for scientific research;
        • Experience with petabyte-scale data management and massively parallel infrastructure highly preferred;
        • Must possess a solid understanding of high-performance computing architectures and technologies;
        • Must possess a strong customer service orientation;
        • Ability to oversee environments requiring high levels of security and regulatory compliance, including HIPAA;
        • Experience with protected health information or personally-identifiable information is a plus;
        • Experience in a computational biology and bioinformatics setting is a plus but not essential;
        • Excellent leadership and exceptional verbal and written communication skills;
        • Ability to provide technical depth, but also communicate the “big picture” to non-scientific stakeholders, is essential.
        APPLY
    • Sequencing Operations

      NYGC is committed to providing the most advanced sequencing an analysis possible. Our facility was designed to accommodate ever-improving technology, and we have more sequencing capacity than any other single institution in the Tri-State area. The Sequencing Operations group is responsible for understanding and interpreting sequencing and primary bioinformatics data, and is central to the transformative work of NYGC.
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        Laboratory Inventory Associate

        Job Description

        The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

        Position Description

        We are looking for a highly motivated, independent, but team-oriented Laboratory Inventory Associate to join our existing and growing inventory management team. This position will support the laboratory director with inventory management services, as well as other general support as outlined below.

        Job duties will include, but are not limited to:

        • Track laboratory material levels, lots, and expiration dates;
        • Assist in establishing and adjusting necessary minimum and maximum inventory quantities for each inventory item based on actual and forecasted usage;
        • Establish and maintain good relations with all reagent vendors and help with price negotiations;
        • Place orders for needed consumables and reagents;
        • Conduct purchase order follow-up while trouble-shooting and expediting, and act as the first point of contact;
        • Work closely with the laboratory management team to ensure proper stocking of laboratories;
        • Provide weekly inventory reporting;
        • Periodically analyze inventory reports for trends that will affect reorder points and adjust as necessary;
        • Set up and monitor standing orders and shipments, and make changes to schedules as needed;
        • Receiving and unpacking of consumable, samples, and reagents;
        • Maintaining stock and freezer rooms;
        • Stocking of laboratories;
        • Prepare sample racks and tubes for shipment to customers;
        • Handle sample shipment;
        • Assist in various other projects as needed such as barcoding/labeling of plastic ware/containers;
        • Autoclaving and glass washing.

        Required Skills

        • High school diploma;
        • Familiarity with Microsoft Word, Excel, and PowerPoint, preferably with Mac OS;
        • Previous experience as lab support, stockroom attendant, materials management, or procurement is a plus, especially previous experience in a laboratory environment;
        • Good organizational skills, including the ability to work independently and efficiently, are essential;
        • Ability to multitask is a must, along with an orientation toward teamwork and cooperation;
        • Ability to lift up to 50 lbs;
        • Excellent communication skills required.

        Job Location

        New York, New York, United States

        Position Type

        Full-Time/Regular

        APPLY
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        Staff Scientist, Clinical Laboratory

        Job Description

        The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

        Position Description

        The New York Genome Center Clinical Laboratory is looking for a Staff Scientist to assist with data analysis and interpretation of variants.

        Essential responsibilities include the following (other duties may be assigned):

        • Assist with analysis, review and interpretation of sanger sequencing data;
        • Investigate the clinical significance of variants found in sequencing-based assays – search online mutation databases and published literature;
        • Review disease and phenotype data;
        • Maintain internal variant databases for different assay/disease areas;
        • Assist in preparing clinical reports and perform additional duties when necessary.

        Required Skills

        • PhD. in biology, genetics, biochemistry, or a related field;
        • ABMGG training preferred with 2 years of experience in a clinical laboratory;
        • Strong scientific background, including nucleic acid biology and biochemistry;
        • Thrives in a fast-paced, rapidly changing, start-up like environment;
        • Self-motivated and capable of analyzing and solving complex problems through innovative thought and experience;
        • Excellent general laboratory and organizational skills, including the ability to work independently with minimal supervision and to train others in laboratory methods.

        Job Location

        New York, New York, United States

        Position Type

        Full-Time/Regular

         

        APPLY
    • Software Engineering

      Our Software Engineers develop cutting edge tools to drive the services at NYGC. This team works closely with bioinformatics, sequencing lab, scientists, program management, and more to develop scientific applications for high-volume data processing, analysis and management.
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        Senior Software Engineer (I, II, Principal or Senior Principal)

        Job Description

        The full-time Software Engineer (I, II, Principal or Senior Principal) role will be responsible for back-end hands-on development of applications, services and pipelines while also providing technical leadership and project oversight.

        Opportunity to be involved from the ground up on two or more new projects that will soon be underway:

        • Clinical Lab Specimen Requisition & Accessioning System
        • e-Science Cloud
        • Molecular Data Submission Pipeline

        Essential job functions will include:

        • Develop, test, document, deploy and support production-quality software in a timely fashion
        • Develop in-depth knowledge and expertise of the project problem domain
        • Uphold best practices for self-documenting code and participate in code review sessions
        • Collaborate with users, stakeholders, fellow Software Engineers and System Administrators

        Position Requirements

        Basic:

        • Bachelor’s degree in Computer Science or related discipline
        • Eight (8) or more years’ relevant work experience as a Software Engineer
        • Ability to thrive in uncertainty
        • Must be able to work in a fast-paced start-up like environment
        • One or more years’ experience with Java 1.7 or higher
        • One or more years’ experience with RDMS and/or NoSQL document-based data stores

        Preferred:

        • RESTful Web Services using JSON
        • Tomcat, JBoss or GlassFish
        • Log4J
        • Gradle or Maven
        • ORM Framework (e.g., ORMLite, MyBatis, jOOQ, JPA, Hibernate)
        • Version control and source code management systems (e.g. Git, SVN)
        • Batch scheduled high throughput computing using queuing systems (e.g. SGE or LSF)
        • RESTful API Modeling Language (RAML)
        • Unix / Linux and VM environments
        • Encryption and data privacy
        • Continuous Integration
        • Functional Programming
        • Issue & Project Tracking (e.g. JIRA)
        • Java 1.8

        Job Location

        New York, New York, United States

        Position Type

        Full-Time/Regular

         

        APPLY
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        Software Engineer (I or II)

        Job Description

        The full-time Software Engineer (I or II) role will be responsible for back-end hands-on development of applications, services and pipelines.

        Take ownership of enhancing, maintaining and supporting our Laboratory Sample Storage Management System while also having the opportunity to contribute significantly to one or more new projects that will soon be underway:

        • Clinical Lab Specimen Requisition & Accessioning System
        • eScience Cloud
        • Molecular Data Submission Pipeline

        Essential job functions will include:

        • Develop, test, document, deploy and support production-quality software in a timely fashion
        • Develop in-depth knowledge and expertise of the project problem domain
        • Uphold best practices for self-documenting code and participate in code review sessions
        • Collaborate with users, stakeholders, fellow Software Engineers and System Administrators

        Position Requirements

        Basic:

        • Bachelor’s degree in Computer Science or related discipline
        • Two (2) or more years’ relevant work experience as a Software Engineer
        • Ability to thrive in uncertainty
        • Must be able to work in a fast-paced start-up like environment
        • One or more years’ experience with Java 1.7 or higher
        • One or more years’ experience with RDMS and/or NoSQL document-based data stores

        Preferred:

        • RESTful Web Services using JSON
        • Tomcat, JBoss or GlassFish
        • Log4J
        • Gradle or Maven
        • ORM Framework (e.g., ORMLite, MyBatis, jOOQ, JPA, Hibernate)
        • Version control and source code management systems (e.g. Git, SVN)
        • Batch scheduled high throughput computing using queuing systems (e.g. SGE or LSF)
        • RESTful API Modeling Language (RAML)
        • Unix / Linux and VM environments
        • Encryption and data privacy
        • Continuous Integration
        • Functional Programming
        • Issue & Project Tracking (e.g. JIRA)
        • Java 1.8

        Salary: Dependent on education and experience (Software Engineer I: $70-80,000, Software Engineer II: $85,000-95,000)

        Job Location

        New York, New York, United States

        Position Type

        Full-Time/Regular

         

        APPLY
    • Technology Innovation

      Our Innovation Lab is currently testing several novel technologies with the potential to complement and enhance current technologies. Working with this group provides the opportunity to be on the cutting-edge of new technology and to perform innovative research that will shape the future of our industry.