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OPPORTUNITIES

  • Academic

    Each faculty member of the NYGC leads a laboratory of post doctoral researchers, lab associates and scientific staff. They integrate their genomic expertise with the work that we are doing NYGC, working in collaborative research relationships both inside NYGC and with academic institutions. Our Faculty members hold joint appointments at our Institutional Founding Members while also managing their independent laboratories housed at the NYGC and conducting ground-breaking and collaborative genomic research.
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      Junior Faculty Appointment in Human Genetics and Genomics at the New York Genome Center

      The New York Genome Center (NYGC) invites applications for a Core Junior Faculty Member position in all areas of human genetics or genomics. We encourage applicants who seek to design innovative approaches to analyze and interpret human genetic and genomic data, advance personalized and precision medicine, develop new methods in statistical or population genetics, or to understand the genetic underpinnings of clinical phenotypes. The candidate’s research interests should synergize with the highly collaborative environment at NYGC, including diverse Faculty, Computational Biology and Innovation Labs. NYGC Faculty have access to significant computational resources and sequencing infrastructure, and are encouraged to interact and collaborate across the New York research community. A Core Faculty Member appointment at NYGC is typically coupled with a tenure-track faculty appointment with one of the partner universities, as negotiated during the recruitment process.

      The NYGC Faculty comprises an exceptional group of primary basic science faculty with research interests spanning human genetics, computational biology, genomics, developmental biology, single cell analysis, epigenetics, and genome engineering (http://www.nygenome.org/lab-groups-overview/). Faculty hold joint appointments with departments at NYC-area universities, such as Cornell University, Columbia University, and New York University. Candidates must hold a Ph.D., M.D., or equivalent degree, and have an outstanding research record. Applications can be uploaded through https://academicjobsonline.org/ajo/jobs/10499/. Applications should include a cover letter, a curriculum vitae, a description of previous research (1 page), a concise statement of research plans (up to 2 pages), reprints of two publications and three letters of reference. We strongly encourage applications from minorities, women, protected veterans and individuals with disabilities. Application materials should be uploaded before December 31, but the position will remain open until filled. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

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      Postdoctoral Researcher, Lappalainen Lab

      Job Description

      About the New York Genome Center

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      Dr. Tuuli Lappalainen’s research group is looking for a postdoctoral researcher to work on projects in computational genetics and functional genomics.

      The Lappalainen Lab (http://tllab.org) studies genetic variation in human populations affecting molecular, cellular, and high-level traits and diseases. We use both computational and experimental methods to study these questions, with an interdisciplinary integration of approaches from computational genetics, population genetics, functional genomics, and molecular genetics. Our particular focus is on integration of large-scale genome and transcriptome sequencing data sets. We are part of several large consortia, including GTEx and MoTrPAC.

      We are looking for a computational postdoc to join our team (currently 8 people). Possible projects include, but are not limited to, genetic and environmental interactions on functional effects of genetic variants, methods development to integrate genetic data with molecular and high-level phenotype data sets, and population genetics of regulatory variation in humans.

      Required Skills

      • PhD in human genetics, functional genomics, or a related field;
      • Strong quantitative skills including proficiency in at least one programming language;
      • Experience of analysis of large-scale data sets is essential.
      • A publication record;
      • Excellent organization and communication skills, along with a high degree of independence and flexibility to thrive in a novel and rapidly changing research environment.

      Please include the following items with your application: 1) CV with a list of publications and preprints, 2) a one-page summary of your present and future research interests, 3) a list of three references and their contact information.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

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      Postdoctoral Associate, Sanjana Lab

      Job Description

      The Sanjana Lab at the New York Genome Center and NYU’s Department of Biology and Center for Genomics and Systems Biology is looking for an energetic and motivated individual to work as a Postdoctoral Associate within a highly creative and dynamic research team of scientists, engineers, and life science entrepreneurs.

      The Sanjana lab works at the intersection of genomics, bioengineering and neuroscience. We are curious about many things and are passionate about what we do. We primarily develop new technologies for hacking and understanding biological systems. We try to learn from nature and to re-purpose what we learn to gain deeper insights into how genomes and neural systems function. In the lab, we modify genomes, perform high-throughput screens, differentiate human neurons from stem cells, watch synapses rewire, find vulnerabilities in cancer cells and have a lot of fun in the process. We aim to have a tangible impact on improving human health by creating new biological tools and fundamental biological discovery.

      Please include the following items with your application: 1) CV with a list of publications;   2) a short summary of your present and future research interests;   3) a list of three references and their contact information.

      Required Skills

      The ideal candidate will hold a PhD or MD-PhD, have prior research experience in molecular biology, chemistry, biochemistry, neuroscience, cancer biology and/or genomics and prior peer-reviewed publications. The candidate will be expected to plan and carry out research tasks independently and write-up/present findings on a regular basis.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

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  • Administration

    We believe that every team member is crucial as NYGC works towards our mission, be it in a scientific, technical, or administrative position. Our administration team plays a huge role in driving transformative change in biomedical and clinical care. This group includes external affairs, finance, legal, business development, project management, sponsored research and facilities.
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      Director, Research Administration

      Job Description

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      The Director, Research Administration will create an environment and culture that provides growth opportunities for genomics related research through excellence in administration of grants and sponsored research for the New York Genome Center, including managing all aspects of pre- and post-award activities and research compliance.  The incumbent serves as a resource for principal investigators and scientific staff through identifying, facilitating and supporting all applications and awards for extramural funding. The Director will provide excellent leadership and people management, including mentoring, coaching, training, developing and building teams.

      Grants Administration and Sponsored Research responsibilities include, but are not limited to:

      • Oversee the preparation of applications and the establishment of resources to ensure complete, accurate, and timely submission of grants and contracts:
        • Identify funding sources and funding search mechanisms, convey information within NYGC concerning wide varieties of funding opportunities (including research specific and career path and career stage specific opportunities);
        • Provide technical support needed to write and submit proposals: research and review proposals and note technical requirements; develop formats and samples of budgets for proposals; advise on proposal formats based on review of the request for proposal; submit proposals to funding agencies and initiate all the required registrations, assurances; and signature requirements;
        • Communicate interim and final reporting deadlines with PIs and administrative staff and exercising primary responsibility for meeting all funder deadlines and communications requirements;
        • Support budget development for all grants and contracts, including but not limited to, NIH, extramural funding proposals submitted to foundations and for-profit entities;
        • Develop training programs to support grant research and grant proposal writing, and train PIs and other scientific staff to most effectively prepare proposals.
      • Develop administrative procedures that support and streamline grant proposal development, submission and maintenance:
        • Develop and maintain research administration policies, forms and procedures.
        • Lead implementation of grants management system and respective training of NYGC faculty and staff;
        • Lead a process for final internal review and sign-off on extramural funding proposals, budgets, and other sponsored-research related communications;
        • Ensure complementary internal procedures are aligned with Development, Finance, Legal and Project Management to establish workflows that are efficient and prevent duplication of duties.
      • Oversee post-award management of grants:
        • Review all modifications in awards, requests for extensions and revisions in implementation schedules and negotiate with funding agency representatives concerning these matters;
        • Oversee monitoring of spending on sponsored projects and address any budget variances with PI and project management;
        • Prepare and administer all sub-awards to partner institutions and manage sub-recipient monitoring and FFATA reporting.

      Compliance responsibilities include, but are not limited to:

      • Serve as Compliance Officer, including being responsible for research compliance related education, training and disclosures and working directly with the Compliance Project Manager;
      • Manage Compliance Working group, serve as Chair of the Conflict of Interest Committee and act as NYGC Privacy Officer;
      • Coordinate trainings required for federal compliance on grants and NYGC policies including, but not limited to, conflict of interest, export control, animal subjects, and human subjects;
      • Assist NYGC members to obtain institutional review board (IRB) resources, as needed, to assure compliance with federal regulations;
      • Monitor NYGC’s compliance with all granting agency regulations, and federal rules and regulations;
      • Ensure that the organization understands and meets all compliance requirements related to grant agreements, including mechanisms to properly manage grant obligations;
      • Manage and facilitate the coordination of compliance activities of other departments as it relates to grants.

      Additional responsibilities include:

      • Serve on management committee for all large grants, including participating in all required internal meetings and working closely with project management and finance on financial and compliance matters;
      • Develop and administer the departmental budget, approve and manage expenditure, and forecast short-and long-term budgeting needs;
      • Develop projections of the sponsored research portfolio and provide Finance with all necessary information;
      • Proactively develop collaborative relationships with grant funding representatives.

      Required Skills

      • Undergraduate degree required; Master’s preferred;
      • Certified Research Administrator (CRA) certification preferred;
      • Experience progressively managing Sponsored Research and Compliance functions;
      • Experience in people management;
      • Experience in pre- and post-award activity required;
      • Experience in scientific research, health, and/or university environment, required;
      • Extensive experience with research compliance, knowledge of federal agency practices, regulations and policies, and evidence of leadership success in comparable situations;
      • Extensive knowledge and understanding of federal regulations and agency guidelines for grants management and sponsored research, NIH required; NSF, US DOE, and US DOD experience preferred;
      • Ability to excel at working effectively, collaboratively, and diplomatically with PIs and senior administrators;
      • Knowledge of grants accounting and procurement best practices;
      • Ability to work with program officers at federal and state agencies and act as effective liaison between PIs/research staff and funding agencies;
      • Proven ability to manage budgets;
      • Interest and motivation to dramatically grow the sponsored research portfolio over the next 2-3 years.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

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  • Bioinformatics

    We are proud to boast a world-class bioinformatics and computational biology organization to support the cutting edge genomics research and integrated genomics services that we offer at NYGC. Our collaborative bioinformatics team is passionate about understanding and modeling human genetic variation and researching how it can be used to generate clinically actionable results.
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      Bioinformatics Scientist, Cancer Genomics

      Job Description

      The New York Genome Center is looking for a highly motivated individual to join our computational biology group. As Bioinformatics Scientist, you will be responsible for handling of custom analysis and reporting for NYGC staff and collaborators. You will also share technical responsibility for the maintenance, benchmarking, and continuous improvement of our cancer genome analysis pipelines. You will collaborate with analysts and programmers performing development and analysis in this area. You should have significant experience in cancer genomics, including familiarity with commonly used algorithms for alignment, variant calling, and structural variant calling. Expertise in one or more common disease areas would be ideal. Collaboration with other members of the computational biology team as well as external collaborators and customers is paramount. Examples of recent projects involve tumor evolution, tumor heterogeneity, liquid biopsy, and prediction of personalized treatments (such as targeted therapies or immunotherapy). Publication of developed methods and scientific findings is encouraged. 

      Job duties will include, but may not be limited to:

      • Contribute to setup, management and maintenance of next generation sequencing (NGS) data analysis pipelines;
      • Analyze sequencing data using the established pipeline(s);
      • Stay current on innovations in DNA sequencing analysis;
      • Develop and implement innovative computational approaches for the analysis of large sequence datasets from NGS technologies;
      • Collaborate and consult with external and internal researchers on the analyses of NGS data;
      • Interpret and present the results of the computational and statistical analyses to collaborators and coworkers;
      • Work with the software engineering team to ensure pipeline upgrades and new pipelines are properly implemented in our production workflow manager;
      • Assist collaborators with data access, analysis, and interpretation;
      • Supervise and guide bioinformatics analysts/programmers;
      • Participate in grant application writing;
      • Publish results in scientific journals and give presentations at conferences.

      Required Skills

      • PhD in bioinformatics, computational biology, genetics, computer science or similar;
      • 3 or more years work experience in Bioinformatics and Genomics with experience in cancer genomics;
      • Experience managing and working with next generation sequencing data required;
      • Extensive knowledge and experience in the use of existing bioinformatics tools and biological databases, as well as familiarity with cloud computing required;
      • Proficiency in python and R required, and one or more programming languages such as Perl, Java, or C/C++ desirable, as well as willingness to learn new programming languages as necessary to collaborate at NYGC;
      • Experience working in Linux and running tasks in a cluster environment (e.g. SGE) required;
      • Experience working in teams centered around a biological question and with external collaborators required;
      • Excellent written and verbal communication skills required;
      • Experience with design of sequence analysis algorithms desirable.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

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  • IT and Computing

    This group develops and maintains the tools and infrastructure necessary to support our scientists as they tackle ground-breaking and large-scale data and genomic analysis. They are responsible for initiating and fostering external collaborations with technology partners, as well as ensuring that NYGC is a leader in the effective use of technology.
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      Level II – Linux Support Engineer, Research Computing

      Job Description

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      The Level II – Linux Support Engineer will be a part of our rapidly expanding informatics division in supporting the high-performance computing and data storage environment.  This individual will be a member of the research computing team that manages a multi-petabyte data storage system to support a bioinformatics team that analyzes large data sets for genomic research.

      The Level II – Linux Support Engineer will be responsible for the monitoring, movement, cleaning, and manipulation of data and play a key role in data management, data reporting and data pushes.  Job duties will include, but are not limited to, the following:

      • Collaborate with bioinformatics scientists, systems administrators, software engineers, project managers, users, and stakeholders to define requirements and specifications for data analysis workflows, accessing and managing scientific data, and data presentation;
      • Help troubleshoot any existing issues by investigating data flows;
      • Perform and automate data migrations between internal systems, as well as to external sites;
      • Work with internal and external users to suggest and define data locations, and organization;
      • Monitor and report data usage to Senior Management;
      • Track and report on the status of large data transfers;
      • Recommend ways to improve data reliability, efficiency, and quality;
      • Analyze performance and recommend storage solutions by running weekly usage reports;
      • Improve documentation of changing data practices;
      • Interface with Project Managers to ensure smooth data transfer to external collaborators.

      **This is not a Hadoop big data role.

      Required Skills

      • Bachelor’s degree or equivalent work experience;
      • Familiarity with Linux;
      • Familiarity with Command Line;
      • Python and bash scripting experience;
      • Customer service experience, preferred;
      • Life science background and/or experience with sample tracking, is a plus;
      • Excellent communication skills and proven ability to work directly with users to understand their needs and translate those into action plans and system improvements;
      • Proven attention to detail;
      • Must be able to work in a fast-paced, start-up like environment.

      Technologies in Use

      Linux, Isilon, Spectrum Scale (GPFS), Spectrum Archive (LTFSEE), VMWare, Python, Bash, Puppet, Foreman, Cisco UCS, Dell OpenManage, Zabbix, LibreNMS, Git, JIRA, Globus/GridFTP, S3, Google Storage, GridEngine

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

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  • Sequencing Operations

    NYGC is committed to providing the most advanced sequencing an analysis possible. Our facility was designed to accommodate ever-improving technology, and we have more sequencing capacity than any other single institution in the Tri-State area. The Sequencing Operations group is responsible for understanding and interpreting sequencing and primary bioinformatics data, and is central to the transformative work of NYGC.
  • Software Engineering

    Our Software Engineers develop cutting edge tools to drive the services at NYGC. This team works closely with bioinformatics, sequencing lab, scientists, program management, and more to develop scientific applications for high-volume data processing, analysis and management.
  • Technology Innovation

    Our Innovation Lab is currently testing several novel technologies with the potential to complement and enhance current technologies. Working with this group provides the opportunity to be on the cutting-edge of new technology and to perform innovative research that will shape the future of our industry.
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      Research Scientist, Technology Innovation

      Job Description

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond by creating one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, data management, and research.

      Position Description

      The Technology Innovation Lab at NYGC conducts cutting-edge genomics research by leveraging tools and techniques from molecular biology, biological chemistry, and bio-engineering. A Scientist in the Technology Innovation Lab will develop creative protocols for sample and library preparation for Illumina and other next-generation sequencing (NGS) machines, and will push NYGC to the cutting edge of genomics through exploratory research.

      The candidate should be an independent thinker that can develop new protocols and novel schemes to solve complex problems. They will innovate in a revolutionary rather than evolutionary manner. The candidate will be expected to contribute to existing lab projects as well as identify unmet needs in genomics and design new approaches to address them.

      We are looking for candidates with extensive experience in molecular biology; additional experience with biologically-focused chemistry and/or bio-engineering is a plus. Specific responsibilities include, but are not limited to:

      • Monitor developments in sequencing technology and remain on the cutting edge of NGS technology and its many applications;
      • Design novel strategies to prepare samples and libraries for next-generation sequencing platforms, including methods that capture single-cell and multi-modal data, liquid biopsy, ultra-low quantities, long and linked reads, etc.;
      • Master and improve methods on the newest sequencing instruments, as they arrive;
      • Collaborate with new technology providers and provide expertise on next-generation sequencing to maintain NYGC at the forefront of sequencing and genomic analysis;
      • Be a source of knowledge for the team and the rest of the center in applying your skills to solve specific research problems;
      • Maintain significant knowledge of the current, relevant scientific literature, and communicate key developments to other lab members to ensure competitiveness of the group;
      • Publish and present current research through high-impact journals, posters and presentations in a timely manner to the benefit of the research community and to improve the profile of the Center;
      • Take an active part in lab meetings, sharing and improving the knowledge of the team and obtaining information relevant to the team’s goals.

      Required Skills

      • Relevant PhD degree with a strong molecular biology focus. Integration of molecular biology experience with chemistry and/or bio-engineering is preferred; significant post-PhD experience highly preferred;
      • Extensive knowledge and experience of modern molecular biology and/or chemistry tools, including next-generation sequencing methods;
      • A proven track record in innovation and technology development is essential;
      • Ability to work in an independent manner with minimal supervision but having a strong collaborative personality;
      • Excellent communication skills and experience of writing first-author manuscripts for publication – able to present complex data in simple terms;
      • Excellent analytical and organizational skills;
      • Computing skills essential, and bioinformatics experience highly preferred.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

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