Slide background

Slide background
Slide background
Slide background

OPPORTUNITIES

  • Academic

    Each faculty member of the NYGC leads a laboratory of post doctoral researchers, lab associates and scientific staff. They integrate their genomic expertise with the work that we are doing NYGC, working in collaborative research relationships both inside NYGC and with academic institutions. Our Faculty members hold joint appointments at our Institutional Founding Members while also managing their independent laboratories housed at the NYGC and conducting ground-breaking and collaborative genomic research.
    • +
      Junior Faculty Appointment in Human Genetics and Genomics at the New York Genome Center

      The New York Genome Center (NYGC) invites applications for a Core Junior Faculty Member position in all areas of human genetics or genomics. We encourage applicants who seek to design innovative approaches to analyze and interpret human genetic and genomic data, advance personalized and precision medicine, develop new methods in statistical or population genetics, or to understand the genetic underpinnings of clinical phenotypes. The candidate’s research interests should synergize with the highly collaborative environment at NYGC, including diverse Faculty, Computational Biology and Innovation Labs. NYGC Faculty have access to significant computational resources and sequencing infrastructure, and are encouraged to interact and collaborate across the New York research community. A Core Faculty Member appointment at NYGC is typically coupled with a tenure-track faculty appointment with one of the partner universities, as negotiated during the recruitment process.

      The NYGC Faculty comprises an exceptional group of primary basic science faculty with research interests spanning human genetics, computational biology, genomics, developmental biology, single cell analysis, epigenetics, and genome engineering (http://www.nygenome.org/lab-groups-overview/). Faculty hold joint appointments with departments at NYC-area universities, such as Cornell University, Columbia University, and New York University. Candidates must hold a Ph.D., M.D., or equivalent degree, and have an outstanding research record. Applications can be uploaded through https://academicjobsonline.org/ajo/jobs/10499/. Applications should include a cover letter, a curriculum vitae, a description of previous research (1 page), a concise statement of research plans (up to 2 pages), reprints of two publications and three letters of reference. We strongly encourage applications from minorities, women, protected veterans and individuals with disabilities. Application materials should be uploaded before December 31, but the position will remain open until filled. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      APPLY
    • +
      Postdoctoral Researcher, Lappalainen Lab

      Job Description

      About the New York Genome Center

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      Dr. Tuuli Lappalainen’s research group is looking for a postdoctoral researcher to work on projects in computational genetics and functional genomics.

      The Lappalainen Lab (http://tllab.org) studies genetic variation in human populations affecting molecular, cellular, and high-level traits and diseases. We use both computational and experimental methods to study these questions, with an interdisciplinary integration of approaches from computational genetics, population genetics, functional genomics, and molecular genetics. Our particular focus is on integration of large-scale genome and transcriptome sequencing data sets. We are part of several large consortia, including GTEx and MoTrPAC.

      We are looking for a computational postdoc to join our team (currently 8 people). Possible projects include, but are not limited to, genetic and environmental interactions on functional effects of genetic variants, methods development to integrate genetic data with molecular and high-level phenotype data sets, and population genetics of regulatory variation in humans.

      Required Skills

      • PhD in human genetics, functional genomics, or a related field;
      • Strong quantitative skills including proficiency in at least one programming language;
      • Experience of analysis of large-scale data sets is essential.
      • A publication record;
      • Excellent organization and communication skills, along with a high degree of independence and flexibility to thrive in a novel and rapidly changing research environment.

      Please include the following items with your application: 1) CV with a list of publications and preprints, 2) a one-page summary of your present and future research interests, 3) a list of three references and their contact information.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
    • +
      Postdoctoral Associate, Sanjana Lab

      Job Description

      The Sanjana Lab at the New York Genome Center and NYU’s Department of Biology and Center for Genomics and Systems Biology is looking for an energetic and motivated individual to work as a Postdoctoral Associate within a highly creative and dynamic research team of scientists, engineers, and life science entrepreneurs.

      The Sanjana lab works at the intersection of genomics, bioengineering and neuroscience. We are curious about many things and are passionate about what we do. We primarily develop new technologies for hacking and understanding biological systems. We try to learn from nature and to re-purpose what we learn to gain deeper insights into how genomes and neural systems function. In the lab, we modify genomes, perform high-throughput screens, differentiate human neurons from stem cells, watch synapses rewire, find vulnerabilities in cancer cells and have a lot of fun in the process. We aim to have a tangible impact on improving human health by creating new biological tools and fundamental biological discovery.

      Please include the following items with your application: 1) CV with a list of publications;   2) a short summary of your present and future research interests;   3) a list of three references and their contact information.

      Required Skills

      The ideal candidate will hold a PhD or MD-PhD, have prior research experience in molecular biology, chemistry, biochemistry, neuroscience, cancer biology and/or genomics and prior peer-reviewed publications. The candidate will be expected to plan and carry out research tasks independently and write-up/present findings on a regular basis.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
  • Administration

    We believe that every team member is crucial as NYGC works towards our mission, be it in a scientific, technical, or administrative position. Our administration team plays a huge role in driving transformative change in biomedical and clinical care. This group includes external affairs, finance, legal, business development, project management, sponsored research and facilities.
  • Bioinformatics

    We are proud to boast a world-class bioinformatics and computational biology organization to support the cutting edge genomics research and integrated genomics services that we offer at NYGC. Our collaborative bioinformatics team is passionate about understanding and modeling human genetic variation and researching how it can be used to generate clinically actionable results.
    • +
      Bioinformatics Analyst, Molecular Diagnostics

      Job Description

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      The New York Genome Center is looking for a highly motivated, detail-oriented individual to join our Clinical Informatics division within the NYGC Clinical Laboratory. As a Bioinformatics Analyst specializing in molecular diagnostics, you will be responsible for the analysis of next-generation sequencing (NGS) data for hereditary diseases and cancer conformant to CLIA / CLEP guidelines. You will work as part of a team of highly experienced staff and scientists at the NYGC Clinical Laboratory.

      Job duties will include:

      • Analyze sequencing data using established workflows;
      • Perform and evaluate appropriate QC measures;
      • Implement, execute and document data analysis pipelines and workflows;
      • Analyze validation experiments for laboratory developed tests (LDT);
      • Benchmark new tools for sequencing data analysis and propose improvements;
      • Develop and apply novel analysis approaches to aid variant prioritization;
      • Summarize results in written or oral reports for CLIA laboratory personnel;
      • Assist CLIA laboratory personnel in preparing data, text and figures for LDT validation proposals, manuscripts and external presentations.

      Required Skills

      • MS degree with 2+ years’ work/research experience or PhD in bioinformatics, molecular biology, human genetics or related scientific field with demonstrable biomedical informatics skills required;
      • Background in disease-focused genomics;
      • Strong programming skills in Python and shell scripting;
      • Work experience with various sequence analysis tools, including BWA, GATK, Picard, samtools, etc.;
      • Knowledge of CNV analysis and clinical reporting;
      • Familiarity with various QC principles and analysis (e.g., concordance, contamination, standard sequencing QC metrics);
      • Work experience with commonly used public genomics datasets (1000 genomes, ExAC, OMIM, ClinVar, CIViCDB, PharmGKB etc.);
      • Detail-oriented, well-organized;
      • Team oriented with excellent written and verbal communication skills.

      Preferred

      • Prior experience working in CLIA environment is a plus;
      • Experience of benchmarking various analysis tools;
      • Experience of working in a Linux environment, experience with SGE.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
  • IT and Computing

    This group develops and maintains the tools and infrastructure necessary to support our scientists as they tackle ground-breaking and large-scale data and genomic analysis. They are responsible for initiating and fostering external collaborations with technology partners, as well as ensuring that NYGC is a leader in the effective use of technology.
  • Sequencing Operations

    NYGC is committed to providing the most advanced sequencing an analysis possible. Our facility was designed to accommodate ever-improving technology, and we have more sequencing capacity than any other single institution in the Tri-State area. The Sequencing Operations group is responsible for understanding and interpreting sequencing and primary bioinformatics data, and is central to the transformative work of NYGC.
  • Software Engineering

    Our Software Engineers develop cutting edge tools to drive the services at NYGC. This team works closely with bioinformatics, sequencing lab, scientists, program management, and more to develop scientific applications for high-volume data processing, analysis and management.
    • +
      Senior Software Engineer II, Full Stack

      Job Description

      The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

      The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

      Position Description

      We are searching for a software engineer to work on the implementation of a novel data Genomics Data Repository to enable sharing and analysis of genomic and clinical data among researchers, clinicians, genetic counselors, and eventually patients.  The New York Genome Center currently generates about a petabyte of data per month and that rate is expected to increase. The repository referred to here is expected to hold 10s of trillions of rows in single tables, and will be required to respond to large queries both interactively and via APIs.  This position is focused on implementation of the domain application rather than the implemention of the repository itself.   This candidate will be expected to work closely with both database and user interface personnel in carrying out the requirements of this position.

      Essential duties and responsibilities will include, but are not limited to, the following:

      • Collaborate with bioinformatics scientists, clinical researchers and other stakeholders to gather requirements for the genomic and clinical data repository and associated interfaces;
      • Participate in defining overall arcitecture and design for the repository and visuailization product;
      • Work with the UI and visualization team to develop a novel interface allowing physicians to view and understand genomic data test results;
      • Implement the application logic layer and APIs that interface the database and UI to support the application’s core functionality;
      • Build secure interface to clinical and genomic data warehouses at collaborators’ sites to exchange protected health information;
      • Assist with database functionality as needed;
      • Assist with development of other parts of the project as requirements dictate; and,
      • Build and manage secure interfaces for access to restricted data.

      Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

      Required Skills

      Required:

      • BS in Computer Science or related field, or equivalent experience;
      • Minimum of 6 years software engineering experience;
      • Proficiency in Java;
      • Knowledge of JavaScript;
      • Knowledge of SQL required;
      • Experience developing and supporting production-quality software;
      • The ability to produce readable, documented code required, anticipating additions and changes and supporting modifiability and modularity;
      • Interest and willingness to learn about genomics and the infrastructure requirements for supporting genomic sciences, and a desire to work on projects with important. Knowledge of genomics in not necessary; and,
      • Effective written and oral communication skills.

      Preferred:

      • MS in Computer Science, Computer Engineering, or related field;
      • Knowledge of UI frameworks helpful (eg, REACT, Angular, D3) ;
      • Experience as technical lead on production software projects helpful;
      • Experience with large data warehouse applications and big data; and
      • Ability to work in a fast-paced environment and flexibility to work with changing requirements.

      Job Location

      New York, New York, United States

      Position Type

      Full-Time/Regular

       

      APPLY
  • Technology Innovation

    Our Innovation Lab is currently testing several novel technologies with the potential to complement and enhance current technologies. Working with this group provides the opportunity to be on the cutting-edge of new technology and to perform innovative research that will shape the future of our industry.